PMID- 24361294
OWN - NLM
STAT- MEDLINE
DCOM- 20141112
LR  - 20200413
IS  - 1678-4782 (Electronic)
IS  - 0021-7557 (Linking)
VI  - 90
IP  - 2
DP  - 2014 Mar-Apr
TI  - Respiratory allergy to moth: the importance of sensitization to Bombyx mori in 
      children with asthma and rhinitis.
PG  - 176-81
LID - S0021-7557(13)00230-1 [pii]
LID - 10.1016/j.jped.2013.08.009 [doi]
AB  - OBJECTIVE: this study aimed to prepare a silkworm moth (Bombyx mori) antigenic 
      extract and to perform skin prick tests with this extract in patients with 
      allergic respiratory diseases; to evaluate serum specific immunoglobulin E (IgE) 
      to Bombyx mori using ImmunoCAP(R) system and to report the frequency of positivity 
      between the two methods and with clinical data. METHODS: this was a 
      cross-sectional study with 99 children and adolescents diagnosed with asthma 
      and/or allergic rhinitis, who had skin reactivity to at least one of the six 
      aeroallergens tested. Clinical data were evaluated: skin prick tests with Bombyx 
      mori in-house extract, and total and specific IgE analysis using ImmunoCAP(R) were 
      performed. RESULTS: the frequency of Bombyx mori specific IgE was found to be 
      52.5% and 60% using the skin prick test and ImmunoCAP(R), respectively. An 
      association between a positive skin test for Bombyx mori and the presence of 
      allergic rhinitis, atopic dermatitis, and urticaria was observed, but the same 
      was not true for asthma or allergic conjunctivitis. There was no relation with 
      the severity of asthma or rhinitis symptoms. CONCLUSIONS: a high frequency of 
      sensitization to Bombyx mori was observed in a selected population of patients 
      with respiratory allergic diseases in the city of Curitiba, state of Parana, 
      Brazil. The extract prepared from the wings of this moth species is effective in 
      demonstrating this sensitivity.
CI  - Copyright (c) 2013 Sociedade Brasileira de Pediatria. Published by Elsevier Editora 
      Ltda. All rights reserved.
FAU - Araujo, Laura M L
AU  - Araujo LM
AD  - Child and Adolescent Health, Hospital de Clinicas, Universidade Federal do Parana 
      (UFPR), Curitiba, PR, Brazil. Electronic address: laura.araujo80@gmail.com.
FAU - Rosario Filho, Nelson A
AU  - Rosario Filho NA
AD  - Pediatrics, Head of the Allergy and Pediatric Immunology Service, Hospital de 
      Clinicas, Universidade Federal do Parana (UFPR), Curitiba, PR, Brazil.
FAU - Riedi, Carlos A
AU  - Riedi CA
AD  - Pediatrics, Hospital de Clinicas, Universidade Federal do Parana (UFPR), 
      Curitiba, PR, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20131220
PL  - Brazil
TA  - J Pediatr (Rio J)
JT  - Jornal de pediatria
JID - 2985188R
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Allergens/*immunology
MH  - Animals
MH  - Asthma/epidemiology/*immunology
MH  - Bombyx/*immunology
MH  - Brazil
MH  - Child
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Male
MH  - Moths/immunology
MH  - Rhinitis, Allergic
MH  - Rhinitis, Allergic, Perennial/epidemiology/*immunology
MH  - Skin Tests/methods
OTO - NOTNLM
OT  - Asma
OT  - Asthma
OT  - Mariposa
OT  - Moth
OT  - Rhinitis
OT  - Rinite
OT  - Sensibilizacao
OT  - Sensitization
EDAT- 2013/12/24 06:00
MHDA- 2014/11/13 06:00
CRDT- 2013/12/24 06:00
PHST- 2013/06/14 00:00 [received]
PHST- 2013/08/01 00:00 [revised]
PHST- 2013/08/02 00:00 [accepted]
PHST- 2013/12/24 06:00 [entrez]
PHST- 2013/12/24 06:00 [pubmed]
PHST- 2014/11/13 06:00 [medline]
AID - S0021-7557(13)00230-1 [pii]
AID - 10.1016/j.jped.2013.08.009 [doi]
PST - ppublish
SO  - J Pediatr (Rio J). 2014 Mar-Apr;90(2):176-81. doi: 10.1016/j.jped.2013.08.009. 
      Epub 2013 Dec 20.