PMID- 24365031 OWN - NLM STAT- MEDLINE DCOM- 20141104 LR - 20211021 IS - 1478-6362 (Electronic) IS - 1478-6354 (Print) IS - 1478-6354 (Linking) VI - 15 IP - 6 DP - 2013 TI - Synovial fluid CD1c+ myeloid dendritic cells - the inflammatory picture emerges. PG - 128 AB - Dendritic cells (DCs) comprise a heterogeneous group of antigen-presenting cells with many specialized functions, including essential constitutive roles in priming immune and autoimmune responses and in the maintenance of peripheral self-tolerance. At the interface of the innate and adaptive immune systems, they contribute considerably to the production of inflammatory and anti-inflammatory mediators with diverse functions. Emerging evidence suggests that the wide involvement of DCs in immunity and tolerance reflects the function of specialized DC subsets. FAU - Thomas, Ranjeny AU - Thomas R LA - eng PT - Comment PT - Journal Article PL - England TA - Arthritis Res Ther JT - Arthritis research & therapy JID - 101154438 RN - 0 (Antigens, CD1) RN - 0 (Chemokines) RN - 0 (Glycoproteins) SB - IM CON - Arthritis Res Ther. 2013;15(5):R155. PMID: 24286358 MH - Antigens, CD1/*immunology MH - Chemokines/*immunology MH - Dendritic Cells/*immunology MH - Female MH - Glycoproteins/*immunology MH - Humans MH - Lymphocyte Activation/*immunology MH - Male MH - T-Lymphocytes/*immunology MH - T-Lymphocytes, Helper-Inducer/*immunology PMC - PMC3978489 EDAT- 2013/12/25 06:00 MHDA- 2014/11/05 06:00 PMCR- 2013/12/23 CRDT- 2013/12/25 06:00 PHST- 2013/12/25 06:00 [entrez] PHST- 2013/12/25 06:00 [pubmed] PHST- 2014/11/05 06:00 [medline] PHST- 2013/12/23 00:00 [pmc-release] AID - ar4420 [pii] AID - 10.1186/ar4420 [doi] PST - ppublish SO - Arthritis Res Ther. 2013;15(6):128. doi: 10.1186/ar4420.