PMID- 24368540
OWN - NLM
STAT- MEDLINE
DCOM- 20141027
LR  - 20211021
IS  - 1573-6857 (Electronic)
IS  - 0016-6707 (Linking)
VI  - 142
IP  - 1
DP  - 2014 Feb
TI  - Patterns of rDNA and telomeric sequences diversification: contribution to 
      repetitive DNA organization in Phyllostomidae bats.
PG  - 49-58
LID - 10.1007/s10709-013-9753-2 [doi]
AB  - Chromosomal organization and the evolution of genome architecture can be 
      investigated by physical mapping of the genes for 45S and 5S ribosomal DNAs 
      (rDNAs) and by the analysis of telomeric sequences. We studied 12 species of bats 
      belonging to four subfamilies of the family Phyllostomidae in order to correlate 
      patterns of distribution of heterochromatin and the multigene families for rDNA. 
      The number of clusters for 45S gene ranged from one to three pairs, with 
      exclusively location in autosomes, except for Carollia perspicillata that had in 
      X chromosome. The 5S gene all the species studied had only one site located on an 
      autosomal pair. In no species the 45S and 5S genes collocated. The fluorescence 
      in situ hybridization (FISH) probe for telomeric sequences revealed fluorescence 
      on all telomeres in all species, except in Carollia perspicillata. Non-telomeric 
      sites in the pericentromeric region of the chromosomes were observed in most 
      species, ranged from one to 12 pairs. Most interstitial telomeric sequences were 
      coincident with heterochromatic regions. The results obtained in the present work 
      indicate that different evolutionary mechanisms are acting in Phyllostomidae 
      genome architecture, as well as the occurrence of Robertsonian fusion during the 
      chromosomal evolution of bats without a loss of telomeric sequences. These data 
      contribute to understanding the organization of multigene families and telomeric 
      sequences on bat genome as well as the chromosomal evolutionary history of 
      Phyllostomidae bats.
FAU - Calixto, Merilane da Silva
AU  - Calixto Mda S
AD  - Laboratorio de Genetica e Citogenetica Animal, Departamento de Genetica, UFPE - 
      Universidade Federal de Pernambuco, Av. Prof. Moraes Rego, SN. Cidade 
      Universitaria, Recife, PE, CEP 50732-970, Brazil, merilane@gmail.com.
FAU - de Andrade, Izaquiel Santos
AU  - de Andrade IS
FAU - Cabral-de-Mello, Diogo Cavalcanti
AU  - Cabral-de-Mello DC
FAU - Santos, Neide
AU  - Santos N
FAU - Martins, Cesar
AU  - Martins C
FAU - Loreto, Vilma
AU  - Loreto V
FAU - de Souza, Maria Jose
AU  - de Souza MJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131225
PL  - Netherlands
TA  - Genetica
JT  - Genetica
JID - 0370740
RN  - 0 (DNA, Ribosomal)
RN  - 0 (Heterochromatin)
SB  - IM
MH  - Animals
MH  - Centromere
MH  - Chiroptera/classification/*genetics
MH  - Chromosomes, Mammalian
MH  - DNA, Ribosomal/*genetics
MH  - Evolution, Molecular
MH  - *Heterochromatin
MH  - In Situ Hybridization, Fluorescence
MH  - Multigene Family
MH  - Phylogeny
MH  - *Repetitive Sequences, Nucleic Acid
MH  - *Telomere
EDAT- 2013/12/26 06:00
MHDA- 2014/10/28 06:00
CRDT- 2013/12/26 06:00
PHST- 2013/07/01 00:00 [received]
PHST- 2013/12/17 00:00 [accepted]
PHST- 2013/12/26 06:00 [entrez]
PHST- 2013/12/26 06:00 [pubmed]
PHST- 2014/10/28 06:00 [medline]
AID - 10.1007/s10709-013-9753-2 [doi]
PST - ppublish
SO  - Genetica. 2014 Feb;142(1):49-58. doi: 10.1007/s10709-013-9753-2. Epub 2013 Dec 
      25.