PMID- 24372845
OWN - NLM
STAT- MEDLINE
DCOM- 20150709
LR  - 20220317
IS  - 1468-3083 (Electronic)
IS  - 0926-9959 (Print)
IS  - 0926-9959 (Linking)
VI  - 28
IP  - 12
DP  - 2014 Dec
TI  - Psoriasis beyond the skin: an expert group consensus on the management of 
      psoriatic arthritis and common co-morbidities in patients with moderate-to-severe 
      psoriasis.
PG  - 1661-9
LID - 10.1111/jdv.12350 [doi]
AB  - BACKGROUND: Psoriatic arthritis (PsA) and co-morbidities of psoriasis represent a 
      significant clinical and economic burden for patients with moderate-to-severe 
      psoriasis. Often these co-morbidities may go unrecognized or undertreated. While 
      published data are available on the incidence and impact of some of them, 
      practical guidance for dermatologists on detection and management of these 
      co-morbidities is lacking. OBJECTIVE: To prepare expert recommendations to 
      improve the detection and management of common co-morbidities in patients with 
      moderate-to-severe psoriasis. METHODS: A systematic literature review was 
      conducted on some common co-morbidities of psoriasis-cardiovascular (CV) diseases 
      (including obesity, hypertension, hyperglycaemia and dyslipidaemia), 
      psychological co-morbidities (including depression, alcohol abuse and smoking) 
      and PsA-to establish the incidence and impact of each. Data gaps were identified 
      and a Delphi survey was carried out to obtain consensus on the detection and 
      management of each co-morbidity. The expert panel members for the Delphi survey 
      comprised 10 dermatologists with substantial clinical expertise in managing 
      moderate-to-severe psoriasis patients, as well as a cardiologist and a 
      psychologist (see appendix) with an interest in dermatology. Agreement was 
      defined using a Likert scale of 1-7. Consensus regarding agreement for each 
      statement was defined as >/=75% of respondents scoring either 1 (strongly agree) or 
      2 (agree). RESULTS: The expert panel members addressed several topics including 
      screening, intervention, monitoring frequency, and the effects of anti-psoriatic 
      treatment on each co-morbidity. Consensus was achieved on 12 statements out of 22 
      (3 relating to PsA, 4 relating to psychological factors, 5 relating to CV 
      factors). The panel members felt that dermatologists have an important role in 
      screening their psoriasis patients for PsA and in assessing them for 
      psychological and CV co-morbidities. In most cases, however, patients should be 
      referred for specialist management if other co-morbidities are detected. 
      CONCLUSION: This article provides useful and practical guidance for the detection 
      and management of common co-morbidities in patients with moderate-to-severe 
      psoriasis.
CI  - (c) 2013 The Authors. Journal of the European Academy of Dermatology and 
      Venereology published by John Wiley & Sons Ltd on behalf of European Academy of 
      Dermatology and Venereology.
FAU - Strohal, R
AU  - Strohal R
AD  - Department of Dermatology, Federal Academic Teaching Hospital, Feldkirch, 
      Austria.
FAU - Kirby, B
AU  - Kirby B
FAU - Puig, L
AU  - Puig L
CN  - Psoriasis Expert Panel
FAU - Girolomoni, G
AU  - Girolomoni G
FAU - Kragballe, K
AU  - Kragballe K
FAU - Luger, T
AU  - Luger T
FAU - Nestle, F O
AU  - Nestle FO
FAU - Prinz, J C
AU  - Prinz JC
FAU - Stahle, M
AU  - Stahle M
FAU - Yawalkar, N
AU  - Yawalkar N
LA  - eng
PT  - Journal Article
DEP - 20131224
PL  - England
TA  - J Eur Acad Dermatol Venereol
JT  - Journal of the European Academy of Dermatology and Venereology : JEADV
JID - 9216037
SB  - IM
MH  - Delphi Technique
MH  - Humans
MH  - Psoriasis/complications/pathology/*therapy
MH  - Severity of Illness Index
PMC - PMC4258087
EDAT- 2014/01/01 06:00
MHDA- 2015/07/15 06:00
CRDT- 2013/12/31 06:00
PHST- 2013/08/08 00:00 [received]
PHST- 2013/11/18 00:00 [accepted]
PHST- 2013/12/31 06:00 [entrez]
PHST- 2014/01/01 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - 10.1111/jdv.12350 [doi]
PST - ppublish
SO  - J Eur Acad Dermatol Venereol. 2014 Dec;28(12):1661-9. doi: 10.1111/jdv.12350. 
      Epub 2013 Dec 24.