PMID- 24375971 OWN - NLM STAT- MEDLINE DCOM- 20150921 LR - 20161125 IS - 1478-596X (Electronic) IS - 1478-5951 (Linking) VI - 10 IP - 4 DP - 2014 Dec TI - In vitro simulator with numerical stress analysis for evaluation of stent-assisted coiling embolization in cerebral aneurysm treatments. PG - 505-15 LID - 10.1002/rcs.1563 [doi] AB - BACKGROUND: There are several complications associated with Stent-assisted Coil Embolization (SACE) in cerebral aneurysm treatments, due to damaging operations by surgeons and undesirable mechanical properties of stents. Therefore, it is necessary to develop an in vitro simulator that provides both training and research for evaluating the mechanical properties of stents. METHODS: A new in vitro simulator for three-dimensional digital subtraction angiography was constructed, followed by aneurysm models fabricated with new materials. Next, this platform was used to provide training and to conduct photoelastic stress analysis to evaluate the SACE technique. RESULTS: The average interaction stress increasingly varied for the two different stents. Improvements for the Maximum-Likelihood Expectation-Maximization method were developed to reconstruct cross-sections with both thickness and stress information. CONCLUSIONS: The technique presented can improve a surgeon's skills and quantify the performance of stents to improve mechanical design and classification. This method can contribute to three-dimensional stress and volume variation evaluation and assess a surgeon's skills. CI - Copyright (c) 2013 John Wiley & Sons, Ltd. FAU - Shi, Chaoyang AU - Shi C AD - Department of Micro-Nano Systems Engineering, Nagoya University, Japan; Department of Computing, Imperial College London, UK. FAU - Kojima, Masahiro AU - Kojima M FAU - Tercero, Carlos AU - Tercero C FAU - Najdovski, Zoran AU - Najdovski Z FAU - Ikeda, Seiichi AU - Ikeda S FAU - Fukuda, Toshio AU - Fukuda T FAU - Arai, Fumihito AU - Arai F FAU - Negoro, Makoto AU - Negoro M LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20131227 PL - England TA - Int J Med Robot JT - The international journal of medical robotics + computer assisted surgery : MRCAS JID - 101250764 SB - IM MH - Angiography, Digital Subtraction MH - Clinical Competence MH - Computer Simulation MH - Embolization, Therapeutic/*methods MH - Humans MH - Image Processing, Computer-Assisted MH - Imaging, Three-Dimensional MH - Intracranial Aneurysm/diagnostic imaging/*therapy MH - *Stents MH - Stress, Mechanical OTO - NOTNLM OT - Photoelastic stress analysis OT - Stent assisted coil embolization OT - cerebral aneurysm OT - simulator-based training OT - stent EDAT- 2014/01/01 06:00 MHDA- 2015/09/22 06:00 CRDT- 2013/12/31 06:00 PHST- 2013/06/30 00:00 [received] PHST- 2013/11/03 00:00 [revised] PHST- 2013/11/15 00:00 [accepted] PHST- 2013/12/31 06:00 [entrez] PHST- 2014/01/01 06:00 [pubmed] PHST- 2015/09/22 06:00 [medline] AID - 10.1002/rcs.1563 [doi] PST - ppublish SO - Int J Med Robot. 2014 Dec;10(4):505-15. doi: 10.1002/rcs.1563. Epub 2013 Dec 27.