PMID- 24386624
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140103
LR  - 20211021
IS  - 2193-1801 (Print)
IS  - 2193-1801 (Electronic)
IS  - 2193-1801 (Linking)
VI  - 2
DP  - 2013
TI  - Changes in serum BDNF levels associated with moderate-intensity exercise in 
      healthy young Japanese men.
PG  - 678
LID - 10.1186/2193-1801-2-678 [doi]
LID - 678
AB  - PURPOSE: The purpose of this study was to examine the influence of acute 
      moderate-intensity exercise on serum brain-derived neurotrophic factor (BDNF) 
      levels in healthy young Japanese men. BDNF is one of a family of neurotrophic 
      factors involved in neuronal transmission, modulation and plasticity. Previous 
      human-based studies have demonstrated that acute exercise leads to increases in 
      BDNF; however, to date there has been no study conducted among Japanese male 
      subjects. METHODS: Forty young adult Japanese men (aged 24.1 +/- 2.9 years) - 
      reduced to a total of thirty three following subjection to exclusion criteria - 
      performed 30 minutes of exercise at 60% of VO2max on a stationary bicycle. Serum 
      BDNF was analyzed both before and after exercise. RESULTS: Eighteen of the total 
      thirty three subjects demonstrated an increase in serum BDNF after exercise. 
      However, on aggregate, the change in serum BDNF associated with exercise was not 
      significant (p = .17). CONCLUSIONS: This is the first study to demonstrate that 
      serum BDNF levels are not consistently increased by acute moderate-intensity 
      exercise in Japanese men. It is likely that something in the lifestyle and/or 
      environment of male Japanese subjects underlies the difference between our 
      findings and studies conducted in other countries.
FAU - Goda, Akio
AU  - Goda A
AD  - Johns Hopkins School of Medicine, Center for Surgical Trials and Outcomes 
      Research, 600 N. Wolfe Street, Baltimore, MD 21205 USA.
FAU - Ohgi, Shohei
AU  - Ohgi S
AD  - Johns Hopkins School of Medicine, Center for Surgical Trials and Outcomes 
      Research, 600 N. Wolfe Street, Baltimore, MD 21205 USA.
FAU - Kinpara, Kazuhiro
AU  - Kinpara K
AD  - Johns Hopkins School of Medicine, Center for Surgical Trials and Outcomes 
      Research, 600 N. Wolfe Street, Baltimore, MD 21205 USA.
FAU - Shigemori, Kenta
AU  - Shigemori K
AD  - Department of healthcare, Kansai University of Health and welfare science, 
      3-11-1, Asahigaoka, Kashiwara-City, Osaka, 582-0026 Japan.
FAU - Fukuda, Kanji
AU  - Fukuda K
AD  - Department of Rehabilitation, Kinki University School of Medicine, 377-2 
      Ohno-higashi, Osaka-Sayama, Osaka, 589-8511 Japan.
FAU - Schneider, Eric B
AU  - Schneider EB
AD  - Johns Hopkins School of Medicine, Center for Surgical Trials and Outcomes 
      Research, 600 N. Wolfe Street, Baltimore, MD 21205 USA.
LA  - eng
PT  - Journal Article
DEP - 20131218
PL  - Switzerland
TA  - Springerplus
JT  - SpringerPlus
JID - 101597967
PMC - PMC3872285
OTO - NOTNLM
OT  - Aerobic exercise
OT  - Brain-derived neurotrophic factor
OT  - Human
OT  - Japanese
OT  - Physical activity
EDAT- 2014/01/05 06:00
MHDA- 2014/01/05 06:01
PMCR- 2013/12/18
CRDT- 2014/01/04 06:00
PHST- 2013/10/18 00:00 [received]
PHST- 2013/12/13 00:00 [accepted]
PHST- 2014/01/04 06:00 [entrez]
PHST- 2014/01/05 06:00 [pubmed]
PHST- 2014/01/05 06:01 [medline]
PHST- 2013/12/18 00:00 [pmc-release]
AID - 743 [pii]
AID - 10.1186/2193-1801-2-678 [doi]
PST - epublish
SO  - Springerplus. 2013 Dec 18;2:678. doi: 10.1186/2193-1801-2-678. eCollection 2013.