PMID- 24389508 OWN - NLM STAT- MEDLINE DCOM- 20141007 LR - 20140210 IS - 1768-3254 (Electronic) IS - 0223-5234 (Linking) VI - 73 DP - 2014 Feb 12 TI - Biofabrication of silver nanoparticles using Andrographis paniculata. PG - 135-40 LID - S0223-5234(13)00791-5 [pii] LID - 10.1016/j.ejmech.2013.12.004 [doi] AB - New and novel strategies are of recent interest in the development of silver nanoparticles. The plant extracts are eco-friendly, economical and cost effective for synthesis of nanoparticles. In this paper, we represent biofabrication of silver nanoparticles (AgNPs) using Andrographis paniculata and the synthesized AgNPs was monitored by ultra-violet visible spectroscopy (UV-Vis). The morphology and crystalline nature of AgNPs were determined from scanning electron microscopy (SEM) with Energy dispersive X-ray (EDX), X-ray diffraction patterns (XRD), Fourier transform-infrared spectroscopy (FT-IR). The size and the stability were detected by using Nanoparticle analyzer. The average size of the AgNPs was found to be 54 +/- 2 nm and the Zeta potential was found to be -50.7 mV. The synthesized AgNPs have very good antifungal activity. CI - Copyright (c) 2013 Elsevier Masson SAS. All rights reserved. FAU - Kotakadi, Venkata S AU - Kotakadi VS AD - DST-PURSE Centre, Sri Venkateswara University, Tirupati 517502, Andhra Pradesh, India. Electronic address: kotakadi72@gmail.com. FAU - Gaddam, Susmila Aparna AU - Gaddam SA AD - Department of Virology, Sri Venkateswara University, Tirupati 517502, Andhra Pradesh, India. FAU - Subba Rao, Y AU - Subba Rao Y AD - DST-PURSE Centre, Sri Venkateswara University, Tirupati 517502, Andhra Pradesh, India. FAU - Prasad, T N V K V AU - Prasad TN AD - Agricultural Research Station, AN.G.R.A University, Tirupati 517502, Andhra Pradesh, India. FAU - Varada Reddy, A AU - Varada Reddy A AD - Department of Chemistry, Sri Venkateswara University, Tirupati 517502, Andhra Pradesh, India. FAU - Sai Gopal, D V R AU - Sai Gopal DV AD - DST-PURSE Centre, Sri Venkateswara University, Tirupati 517502, Andhra Pradesh, India; Department of Virology, Sri Venkateswara University, Tirupati 517502, Andhra Pradesh, India. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20131216 PL - France TA - Eur J Med Chem JT - European journal of medicinal chemistry JID - 0420510 RN - 0 (Antifungal Agents) RN - 0 (Plant Extracts) RN - 3M4G523W1G (Silver) SB - IM MH - Andrographis/*chemistry MH - Antifungal Agents/*chemical synthesis/chemistry MH - Aspergillus niger/drug effects MH - *Drug Design MH - Drug Stability MH - Metal Nanoparticles/*chemistry MH - Microscopy, Electron, Scanning MH - Oxidation-Reduction MH - Particle Size MH - Penicillium/drug effects MH - Plant Extracts/*chemistry/isolation & purification MH - Silver/*chemistry MH - Spectrophotometry, Ultraviolet MH - Surface Properties MH - X-Ray Diffraction OTO - NOTNLM OT - Antifungal activity OT - Biofabrication OT - EDX OT - FTIR OT - Nanoparticle analyzer OT - Zeta potential EDAT- 2014/01/07 06:00 MHDA- 2014/10/08 06:00 CRDT- 2014/01/07 06:00 PHST- 2012/11/07 00:00 [received] PHST- 2013/09/14 00:00 [revised] PHST- 2013/12/05 00:00 [accepted] PHST- 2014/01/07 06:00 [entrez] PHST- 2014/01/07 06:00 [pubmed] PHST- 2014/10/08 06:00 [medline] AID - S0223-5234(13)00791-5 [pii] AID - 10.1016/j.ejmech.2013.12.004 [doi] PST - ppublish SO - Eur J Med Chem. 2014 Feb 12;73:135-40. doi: 10.1016/j.ejmech.2013.12.004. Epub 2013 Dec 16.