PMID- 24392910
OWN - NLM
STAT- MEDLINE
DCOM- 20140717
LR  - 20151022
IS  - 2325-8179 (Electronic)
IS  - 2325-8160 (Linking)
VI  - 45
IP  - 1
DP  - 2014 Jan-Feb
TI  - The use of spectral-domain optical coherence tomography for differentiating 
      long-standing central retinal artery occlusion and nonarteritic anterior ischemic 
      optic neuropathy.
PG  - 38-44
LID - 10.3928/23258160-20131220-05 [doi]
AB  - BACKGROUND AND OBJECTIVE: To report on the efficacy of macular and optic nerve 
      spectral-domain optical coherence tomography (SD-OCT) in differentiating between 
      long-standing central retinal artery occlusion (CRAO) and nonarteritic anterior 
      ischemic optic neuropathy (NAION). PATIENTS AND METHODS: SD-OCT scans of the 
      macula and optic nerve in 24 patients with unilateral optic atrophy secondary to 
      CRAO (12 patients) and NAION (12 patients) were compared both qualitatively and 
      quantitatively for differentiating features. RESULTS: In patients with 
      long-standing CRAO, there was a significantly greater (P < .001) thinning of the 
      macula relative to the fellow uninvolved eye (-59.7 +/- 31.8 mum) compared to 
      patients with longstanding NAION (-19.9 +/- 8.4 mum) even though both conditions 
      caused a similar (P = .726) degree of peripapillary retinal nerve fiber layer 
      loss (-42.4 +/- 18.5 mum and -44.1 +/- 12.4 mum, respectively). CONCLUSION: SD-OCT 
      macular scans can be used as an adjunctive tool for differentiating between 
      longstanding CRAO and NAION.
CI  - Copyright 2014, SLACK Incorporated.
FAU - Dotan, Gad
AU  - Dotan G
FAU - Goldenberg, Dafna
AU  - Goldenberg D
FAU - Kesler, Anat
AU  - Kesler A
FAU - Naftaliev, Elvira
AU  - Naftaliev E
FAU - Loewenstein, Anat
AU  - Loewenstein A
FAU - Goldstein, Michaella
AU  - Goldstein M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Ophthalmic Surg Lasers Imaging Retina
JT  - Ophthalmic surgery, lasers & imaging retina
JID - 101599215
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Arteritis/diagnosis
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nerve Fibers/pathology
MH  - Optic Nerve/pathology
MH  - Optic Neuropathy, Ischemic/*diagnosis
MH  - Retinal Artery Occlusion/*diagnosis
MH  - Retinal Ganglion Cells/pathology
MH  - Retinal Vessels/pathology
MH  - Tomography, Optical Coherence/*methods
MH  - Visual Acuity
MH  - Visual Fields
EDAT- 2014/01/08 06:00
MHDA- 2014/07/18 06:00
CRDT- 2014/01/08 06:00
PHST- 2013/09/13 00:00 [received]
PHST- 2013/11/04 00:00 [accepted]
PHST- 2014/01/08 06:00 [entrez]
PHST- 2014/01/08 06:00 [pubmed]
PHST- 2014/07/18 06:00 [medline]
AID - 10.3928/23258160-20131220-05 [doi]
PST - ppublish
SO  - Ophthalmic Surg Lasers Imaging Retina. 2014 Jan-Feb;45(1):38-44. doi: 
      10.3928/23258160-20131220-05.