PMID- 24396455
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211021
IS  - 1792-1074 (Print)
IS  - 1792-1082 (Electronic)
IS  - 1792-1074 (Linking)
VI  - 7
IP  - 2
DP  - 2014 Feb
TI  - Metastasis-associated gene 1 promotes invasion and migration potential of 
      laryngeal squamous cell carcinoma cells.
PG  - 399-404
AB  - Overexpression of the metastasis-associated gene 1 (MTA1) has previously been 
      found to be associated with progression of various cancer types to the metastasis 
      stage. The function of MTA1 in laryngeal squamous cell carcinoma (LSCC) remains 
      unclear. To explore the significance of MTA1 in the invasion and migration 
      processes in LSCC, gene transfection and RNA interference (RNAi) were performed 
      to study the biological function of MTA1 in the LSCC cell line, HEP-2. Results 
      showed that MTA1 promoted the invasion, adhesion and migration behavior of LSCC 
      cells. RNAi against MTA1 significantly decreased the malignant phenotypes of 
      cancer cells. MTA1 may be important in the process of LSCC invasion and 
      metastasis.
FAU - Zhang, Haili
AU  - Zhang H
AD  - Department of Otolaryngology Head and Neck Surgery, The First Hospital, Shanxi 
      Medical University, Taiyuan, Shanxi 030001, P.R. China ; State Key Laboratory of 
      Molecular Oncology, Cancer Institute/Cancer Hospital, Chinese Academy of Medical 
      Sciences and Peking Union Medical College, Chao Yang, Beijing 100021, P.R. China.
FAU - Yang, Dong
AU  - Yang D
AD  - State Key Laboratory of Molecular Oncology, Cancer Institute/Cancer Hospital, 
      Chinese Academy of Medical Sciences and Peking Union Medical College, Chao Yang, 
      Beijing 100021, P.R. China.
FAU - Wang, Haijuan
AU  - Wang H
AD  - State Key Laboratory of Molecular Oncology, Cancer Institute/Cancer Hospital, 
      Chinese Academy of Medical Sciences and Peking Union Medical College, Chao Yang, 
      Beijing 100021, P.R. China.
FAU - Wen, Shuxin
AU  - Wen S
AD  - Department of Otolaryngology Head and Neck Surgery, The First Hospital, Shanxi 
      Medical University, Taiyuan, Shanxi 030001, P.R. China.
FAU - Liu, Jian
AU  - Liu J
AD  - State Key Laboratory of Molecular Oncology, Cancer Institute/Cancer Hospital, 
      Chinese Academy of Medical Sciences and Peking Union Medical College, Chao Yang, 
      Beijing 100021, P.R. China.
FAU - Luan, Qingchun
AU  - Luan Q
AD  - State Key Laboratory of Molecular Oncology, Cancer Institute/Cancer Hospital, 
      Chinese Academy of Medical Sciences and Peking Union Medical College, Chao Yang, 
      Beijing 100021, P.R. China.
FAU - Huang, Yixuan
AU  - Huang Y
AD  - State Key Laboratory of Molecular Oncology, Cancer Institute/Cancer Hospital, 
      Chinese Academy of Medical Sciences and Peking Union Medical College, Chao Yang, 
      Beijing 100021, P.R. China.
FAU - Wang, Binquan
AU  - Wang B
AD  - Department of Otolaryngology Head and Neck Surgery, The First Hospital, Shanxi 
      Medical University, Taiyuan, Shanxi 030001, P.R. China.
FAU - Lin, Chen
AU  - Lin C
AD  - State Key Laboratory of Molecular Oncology, Cancer Institute/Cancer Hospital, 
      Chinese Academy of Medical Sciences and Peking Union Medical College, Chao Yang, 
      Beijing 100021, P.R. China.
FAU - Qian, Haili
AU  - Qian H
AD  - State Key Laboratory of Molecular Oncology, Cancer Institute/Cancer Hospital, 
      Chinese Academy of Medical Sciences and Peking Union Medical College, Chao Yang, 
      Beijing 100021, P.R. China.
LA  - eng
PT  - Journal Article
DEP - 20131205
PL  - Greece
TA  - Oncol Lett
JT  - Oncology letters
JID - 101531236
PMC - PMC3881929
OTO - NOTNLM
OT  - invasion
OT  - laryngeal squamous cell carcinoma
OT  - metastasis
OT  - metastasis-associated gene 1
EDAT- 2014/01/08 06:00
MHDA- 2014/01/08 06:01
PMCR- 2013/12/05
CRDT- 2014/01/08 06:00
PHST- 2013/04/28 00:00 [received]
PHST- 2013/11/01 00:00 [accepted]
PHST- 2014/01/08 06:00 [entrez]
PHST- 2014/01/08 06:00 [pubmed]
PHST- 2014/01/08 06:01 [medline]
PHST- 2013/12/05 00:00 [pmc-release]
AID - ol-07-02-0399 [pii]
AID - 10.3892/ol.2013.1729 [doi]
PST - ppublish
SO  - Oncol Lett. 2014 Feb;7(2):399-404. doi: 10.3892/ol.2013.1729. Epub 2013 Dec 5.