PMID- 2440700
OWN - NLM
STAT- MEDLINE
DCOM- 19870917
LR  - 20190624
IS  - 0014-2999 (Print)
IS  - 0014-2999 (Linking)
VI  - 136
IP  - 3
DP  - 1987 Apr 29
TI  - Galanin stimulates growth hormone (GH) secretion via GH-releasing factor (GRF) in 
      conscious rats.
PG  - 415-8
AB  - The possibility of a role of hypothalamic growth hormone (GH)-releasing factor 
      (GRF) in GH secretion induced by centrally administered galanin was investigated 
      in freely moving male rats. Intracerebroventricular (i.c.v.) injection of 
      synthetic galanin (0.4 or 2 micrograms/rat) elicited a dose-related increase in 
      plasma GH in these conscious rats. Pretreatment with rabbit antiserum specific 
      for rat GRF significantly inhibited the plasma GH increase induced by i.c.v. 
      injection of galanin (2 micrograms/rat). These findings suggest that 
      galanin-induced GH secretion in the rat is mediated at least in part by 
      hypothalamic GRF.
FAU - Murakami, Y
AU  - Murakami Y
FAU - Kato, Y
AU  - Kato Y
FAU - Koshiyama, H
AU  - Koshiyama H
FAU - Inoue, T
AU  - Inoue T
FAU - Yanaihara, N
AU  - Yanaihara N
FAU - Imura, H
AU  - Imura H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Eur J Pharmacol
JT  - European journal of pharmacology
JID - 1254354
RN  - 0 (Peptides)
RN  - 88813-36-9 (Galanin)
RN  - 9002-72-6 (Growth Hormone)
RN  - 9034-39-3 (Growth Hormone-Releasing Hormone)
SB  - IM
MH  - Animals
MH  - Galanin
MH  - Growth Hormone/*metabolism
MH  - Growth Hormone-Releasing Hormone/immunology/*physiology
MH  - Immunization, Passive
MH  - Injections, Intraventricular
MH  - Male
MH  - Peptides/*pharmacology
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Time Factors
EDAT- 1987/04/29 00:00
MHDA- 1987/04/29 00:01
CRDT- 1987/04/29 00:00
PHST- 1987/04/29 00:00 [pubmed]
PHST- 1987/04/29 00:01 [medline]
PHST- 1987/04/29 00:00 [entrez]
AID - 0014-2999(87)90316-5 [pii]
AID - 10.1016/0014-2999(87)90316-5 [doi]
PST - ppublish
SO  - Eur J Pharmacol. 1987 Apr 29;136(3):415-8. doi: 10.1016/0014-2999(87)90316-5.