PMID- 24407572
OWN - NLM
STAT- MEDLINE
DCOM- 20141014
LR  - 20181203
IS  - 1525-1438 (Electronic)
IS  - 1048-891X (Linking)
VI  - 24
IP  - 2
DP  - 2014 Feb
TI  - Prognosis of adenosquamous carcinoma compared with adenocarcinoma in uterine 
      cervical cancer: a systematic review and meta-analysis of observational studies.
PG  - 289-94
LID - 10.1097/IGC.0000000000000063 [doi]
AB  - OBJECTIVE: The aim of this study was to compare the survival outcomes of 
      adenosquamous carcinoma (ASC) and adenocarcinoma (AC) of the cervix. METHODS: We 
      searched PubMed and Embase for observational studies that compared the outcomes 
      of 2 histologic subtypes. Hazards ratios (HRs) with 95% confidence intervals 
      (CIs) were calculated with a fixed effects model. RESULTS: A total of 17 studies 
      were included in the analyses. Patients with ASC were associated significantly 
      with poorer overall survival (death HR, 1.27; 95% CI, 1.12-1.43; I(2) = 0%) and 
      recurrence-free survival (recurrence HR, 1.43; 95% CI, 1.05-1.95; I(2) = 19.4%) 
      than those with AC. For clinical stages I and II in particular, ASC predicted 
      significantly poorer outcomes compared with AC (death HR, 1.41; 95% CI, 
      1.17-1.70; I(2) = 0%). CONCLUSIONS: This meta-analysis suggests that ASC may have 
      poorer outcomes compared with AC of the cervix.
FAU - Lee, Jung-Yun
AU  - Lee JY
AD  - *Department of Obstetrics and Gynecology, College of Medicine, Seoul National 
      University; daggerDepartment of Obstetrics and Gynecology, Inje University Sanggye 
      Paik Hospital; and double daggerDepartments of Medicine, and  section signPathology, Seoul National 
      University College of Medicine, Seoul, Korea.
FAU - Lee, Chulmin
AU  - Lee C
FAU - Hahn, Seokyung
AU  - Hahn S
FAU - Kim, Min A
AU  - Kim MA
FAU - Kim, Hee Seung
AU  - Kim HS
FAU - Chung, Hyun Hoon
AU  - Chung HH
FAU - Kim, Jae-Weon
AU  - Kim JW
FAU - Park, Noh Hyun
AU  - Park NH
FAU - Song, Yong-Sang
AU  - Song YS
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PT  - Systematic Review
PL  - England
TA  - Int J Gynecol Cancer
JT  - International journal of gynecological cancer : official journal of the 
      International Gynecological Cancer Society
JID - 9111626
SB  - IM
MH  - Adenocarcinoma/diagnosis/*mortality
MH  - Carcinoma, Adenosquamous/diagnosis/*mortality
MH  - Female
MH  - Humans
MH  - Observational Studies as Topic
MH  - Prognosis
MH  - Uterine Cervical Neoplasms/diagnosis/*mortality
EDAT- 2014/01/11 06:00
MHDA- 2014/10/15 06:00
CRDT- 2014/01/11 06:00
PHST- 2014/01/11 06:00 [entrez]
PHST- 2014/01/11 06:00 [pubmed]
PHST- 2014/10/15 06:00 [medline]
AID - 10.1097/IGC.0000000000000063 [doi]
PST - ppublish
SO  - Int J Gynecol Cancer. 2014 Feb;24(2):289-94. doi: 10.1097/IGC.0000000000000063.