PMID- 24408885
OWN - NLM
STAT- MEDLINE
DCOM- 20141107
LR  - 20220318
IS  - 1873-1953 (Electronic)
IS  - 1474-5151 (Print)
IS  - 1474-5151 (Linking)
VI  - 13
IP  - 2
DP  - 2014 Apr
TI  - Coexisting anxiety and depressive symptoms in patients with heart failure.
PG  - 168-76
LID - 10.1177/1474515113519520 [doi]
AB  - BACKGROUND: Among patients with heart failure (HF), anxiety symptoms may co-exist 
      with depressive symptoms. However, the extent of overlap and risk factors for 
      anxiety symptoms have not been thoroughly described. PURPOSE: The aim of this 
      study was to describe the coexistence of anxiety and depressive symptoms, and to 
      determine the predictors of anxiety symptoms in patients with HF. METHODS: The 
      sample consisted of 556 outpatients with HF (34% female, 62+/-12 years, 54% New 
      York Heart Association (NYHA) class III/IV) enrolled in a multicenter HF quality 
      of life registry. Anxiety symptoms were assessed with the Brief Symptom 
      Inventory-anxiety subscale. Depressive symptoms were measured with the Beck 
      Depression Inventory-II (BDI). We used a cut-point of 0.35 to categorize patients 
      as having anxiety symptoms or no anxiety symptoms. Logistic regression was used 
      to determine whether age, gender, minority status, educational level, functional 
      status, comorbidities, depressive symptoms, and antidepressant use were 
      predictors of anxiety symptoms. RESULTS: One-third of patients had both 
      depressive and anxiety symptoms. There was a dose-response relationship between 
      depressive symptoms and anxiety symptoms; higher levels of depressive symptoms 
      were associated with a higher level of anxiety symptoms. Younger age (odds ratio 
      (OR)= 0.97, p=0.004, 95% confidence interval (CI) 0.95-0.99) and depressive 
      symptoms (OR =1.25, p<0.001, 95% CI 1.19-1.31) were independent predictors of 
      anxiety symptoms. CONCLUSIONS: Patients with HF and depressive symptoms are at 
      high risk for experiencing anxiety symptoms. Clinicians should assess these 
      patients for comorbid anxiety symptoms. Research is needed to test interventions 
      for both depressive and anxiety symptoms.
FAU - Dekker, Rebecca L
AU  - Dekker RL
AD  - 1College of Nursing, University of Kentucky, USA.
FAU - Lennie, Terry A
AU  - Lennie TA
FAU - Doering, Lynn V
AU  - Doering LV
FAU - Chung, Misook L
AU  - Chung ML
FAU - Wu, Jia-Rong
AU  - Wu JR
FAU - Moser, Debra K
AU  - Moser DK
LA  - eng
GR  - R01 NR009280/NR/NINR NIH HHS/United States
GR  - P20 NR 010679/NR/NINR NIH HHS/United States
GR  - K23 NR014489/NR/NINR NIH HHS/United States
GR  - R01 NR 008567/NR/NINR NIH HHS/United States
GR  - K23 NR013480/NR/NINR NIH HHS/United States
GR  - M01 RR002602/RR/NCRR NIH HHS/United States
GR  - P20 NR010679/NR/NINR NIH HHS/United States
GR  - R01 NR 009280/NR/NINR NIH HHS/United States
GR  - M01RR02602/RR/NCRR NIH HHS/United States
GR  - R01 NR008567/NR/NINR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20140109
PL  - England
TA  - Eur J Cardiovasc Nurs
JT  - European journal of cardiovascular nursing
JID - 101128793
SB  - IM
MH  - Aged
MH  - Anxiety/epidemiology/nursing/*psychology
MH  - Cardiovascular Nursing/*methods
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Depression/epidemiology/nursing/*psychology
MH  - Female
MH  - Heart Failure/epidemiology/nursing/*psychology
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Outpatients/psychology
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Psychological Tests
MH  - Quality of Life/psychology
MH  - Registries
MH  - Risk Factors
PMC - PMC3992982
MID - NIHMS563719
OTO - NOTNLM
OT  - Cardiovascular
OT  - anxiety disorder
OT  - depressive disorder
OT  - heart failure
EDAT- 2014/01/11 06:00
MHDA- 2014/11/08 06:00
PMCR- 2015/04/01
CRDT- 2014/01/11 06:00
PHST- 2014/01/11 06:00 [entrez]
PHST- 2014/01/11 06:00 [pubmed]
PHST- 2014/11/08 06:00 [medline]
PHST- 2015/04/01 00:00 [pmc-release]
AID - 1474515113519520 [pii]
AID - 10.1177/1474515113519520 [doi]
PST - ppublish
SO  - Eur J Cardiovasc Nurs. 2014 Apr;13(2):168-76. doi: 10.1177/1474515113519520. Epub 
      2014 Jan 9.