PMID- 24411286 OWN - NLM STAT- MEDLINE DCOM- 20140421 LR - 20161125 IS - 1879-1913 (Electronic) IS - 0002-9149 (Linking) VI - 113 IP - 5 DP - 2014 Mar 1 TI - Comparison between ultrasound-guided compression and para-aneurysmal saline injection in the treatment of postcatheterization femoral artery pseudoaneurysms. PG - 871-6 LID - S0002-9149(13)02387-4 [pii] LID - 10.1016/j.amjcard.2013.11.042 [doi] AB - Management of postcatheterization femoral artery pseudoaneurysm (FAP) is problematic. Ultrasound-guided compression (UGC) is painful and cumbersome. Thrombin injection is costly and may cause thromboembolism. Ultrasound-guided para-aneurysmal saline injection (PASI) has been described but was never compared against other treatment methods of FAP. We aimed at comparing the success rate and complications of PASI versus UGC. We randomly assigned 80 patients with postcatheterization FAPs to either UGC (40 patients) or PASI (40 patients). We compared the 2 procedures regarding successful obliteration of the FAP, incidence of vasovagal attacks, procedure time, discontinuation of antiplatelet and/or anticoagulants, and the Doppler waveform in the ipsilateral pedal arteries at the end of the procedure. There was no significant difference between patients in both groups regarding clinical and vascular duplex data. The mean durations of UGC and PASI procedures were 58.14 +/- 28.45 and 30.33 +/- 8.56 minutes, respectively (p = 0.045). Vasovagal attacks were reported in 10 (25%) and 2 patients (5%) treated with UGC and PASI, respectively (p = 0.05). All patients in both groups had triphasic Doppler waveform in the infrapopliteal arteries before and after the procedure. The primary and final success rates were 75%, 92.5%, 87.5%, and 95% for UGC and PASI, respectively (p = 0.43). In successfully treated patients, there was no reperfusion of the FAP in the follow-up studies (days 1 and 7) in both groups. In conclusion, ultrasound-guided PASI is an effective method for the treatment of FAP. Compared with UGC, PASI is faster, less likely to cause vasovagal reactions, and can be more convenient to patients and physicians. CI - Copyright (c) 2014 Elsevier Inc. All rights reserved. FAU - ElMahdy, Mahmoud Farouk AU - ElMahdy MF AD - Department of Cardiovascular Medicine, Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo, Egypt. FAU - Kassem, Hussien Heshmat AU - Kassem HH AD - Department of Cardiovascular Medicine, Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo, Egypt. Electronic address: hheshmat@kasralainy.edu.eg. FAU - Ewis, Essam Baligh AU - Ewis EB AD - Department of Cardiovascular Medicine, Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo, Egypt. FAU - Mahdy, Soliman Gharieb AU - Mahdy SG AD - Department of Cardiovascular Medicine, Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo, Egypt. LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial DEP - 20131212 PL - United States TA - Am J Cardiol JT - The American journal of cardiology JID - 0207277 RN - 0 (Hemostatics) RN - 451W47IQ8X (Sodium Chloride) RN - EC 3.4.21.5 (Thrombin) SB - IM MH - Administration, Cutaneous MH - Aneurysm, False/diagnostic imaging/*therapy MH - Cardiac Catheterization/adverse effects MH - Female MH - *Femoral Artery/diagnostic imaging MH - *Hemostatic Techniques MH - Hemostatics/administration & dosage MH - Humans MH - Male MH - Middle Aged MH - *Pressure MH - Punctures/adverse effects MH - Sodium Chloride/*administration & dosage MH - Thrombin/administration & dosage MH - Treatment Outcome MH - Ultrasonography, Doppler, Color MH - Ultrasonography, Interventional EDAT- 2014/01/15 06:00 MHDA- 2014/04/22 06:00 CRDT- 2014/01/14 06:00 PHST- 2013/06/12 00:00 [received] PHST- 2013/11/12 00:00 [revised] PHST- 2013/11/12 00:00 [accepted] PHST- 2014/01/14 06:00 [entrez] PHST- 2014/01/15 06:00 [pubmed] PHST- 2014/04/22 06:00 [medline] AID - S0002-9149(13)02387-4 [pii] AID - 10.1016/j.amjcard.2013.11.042 [doi] PST - ppublish SO - Am J Cardiol. 2014 Mar 1;113(5):871-6. doi: 10.1016/j.amjcard.2013.11.042. Epub 2013 Dec 12.