PMID- 24420418
OWN - NLM
STAT- MEDLINE
DCOM- 20141024
LR  - 20211021
IS  - 1875-8312 (Electronic)
IS  - 1569-5794 (Linking)
VI  - 30
IP  - 2
DP  - 2014 Feb
TI  - ST elevation acute myocardial infarction accelerates non-culprit coronary lesion 
      atherosclerosis.
PG  - 253-61
LID - 10.1007/s10554-013-0354-z [doi]
AB  - The previously study found, using a mouse model, that acute myocardial infarction 
      accelerated atherosclerosis. This study assessed whether ST elevation myocardial 
      infarction (STEMI) accelerates the progression of non-culprit coronary lesion 
      (NCCL) in patients who underwent percutaneous coronary interventions (PCI). Four 
      hundred and forty-nine patients who underwent successful PCI with stents and 
      follow-up coronary angiography in a single center were enrolled. The NCCL 
      progression was assessed using three-dimensional quantitative coronary 
      angiography and was defined as >/=10 % diameter reduction of a preexisting stenosis 
      >/=50, >/=30 % diameter reduction of a stenosis <50 %, development of a new stenosis 
      >/=30 % in a previously normal segment, or progression to total occlusion. The 
      patients were classified into two groups according to whether the progression 
      existed or not. The median age of patients was 58.4 years. The mean angiographic 
      follow-up period was 12.3 months, 134 (29.8 %) patients had NCCL progression. 
      Multivariate Cox regression analysis (step-wise) showed that STEMI was the only 
      independent determinant of NCCL progression. Compared to the other coronary 
      artery disease group, the crude hazard ratio (HR) of NCCL progression for the 
      STEMI group was 3.20 (95 % CI 2.27-4.50; p < 0.001), and the association remained 
      significantly after adjustment for age, sex, BMI, SBP, DBP, serum lipids, fasting 
      blood glucose, peak monocyte count, smoking, drinking, hypertension, diabetes 
      mellitus and lesion characteristics of NCCL (adjusted HR 3.56, 95 % CI 2.41-5.27; 
      p < 0.001). The ST elevation acute myocardial infarction accelerates non-culprit 
      coronary lesion atherosclerosis.
FAU - Han, Yunfeng
AU  - Han Y
AD  - Department of Cardiology, Chinese PLA General Hospital, Beijing, China.
FAU - Jing, Jing
AU  - Jing J
FAU - Tu, Shengxian
AU  - Tu S
FAU - Tian, Feng
AU  - Tian F
FAU - Xue, Hao
AU  - Xue H
FAU - Chen, Weiren
AU  - Chen W
FAU - Chen, Jinsong
AU  - Chen J
FAU - Reiber, Johan H C
AU  - Reiber JH
FAU - Chen, Yundai
AU  - Chen Y
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20140114
PL  - United States
TA  - Int J Cardiovasc Imaging
JT  - The international journal of cardiovascular imaging
JID - 100969716
SB  - IM
MH  - Aged
MH  - Chi-Square Distribution
MH  - China
MH  - Coronary Angiography
MH  - Coronary Artery Disease/*complications/diagnosis/therapy
MH  - Coronary Occlusion/diagnosis/*etiology
MH  - Coronary Stenosis/*complications/diagnosis/therapy
MH  - Disease Progression
MH  - Female
MH  - Humans
MH  - Imaging, Three-Dimensional
MH  - Kaplan-Meier Estimate
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Myocardial Infarction/diagnosis/*etiology/therapy
MH  - *Percutaneous Coronary Intervention/instrumentation
MH  - Predictive Value of Tests
MH  - Proportional Hazards Models
MH  - Radiographic Image Interpretation, Computer-Assisted
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Stents
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2014/01/15 06:00
MHDA- 2014/10/25 06:00
CRDT- 2014/01/15 06:00
PHST- 2013/09/27 00:00 [received]
PHST- 2013/12/23 00:00 [accepted]
PHST- 2014/01/15 06:00 [entrez]
PHST- 2014/01/15 06:00 [pubmed]
PHST- 2014/10/25 06:00 [medline]
AID - 10.1007/s10554-013-0354-z [doi]
PST - ppublish
SO  - Int J Cardiovasc Imaging. 2014 Feb;30(2):253-61. doi: 10.1007/s10554-013-0354-z. 
      Epub 2014 Jan 14.