PMID- 24423813
OWN - NLM
STAT- MEDLINE
DCOM- 20150701
LR  - 20181202
IS  - 1532-2750 (Electronic)
IS  - 1098-612X (Linking)
VI  - 16
IP  - 10
DP  - 2014 Oct
TI  - Medical management and monitoring of the hyperthyroid cat: a survey of UK general 
      practitioners.
PG  - 788-95
LID - 10.1177/1098612X13519633 [doi]
AB  - Feline hyperthyroidism is commonly diagnosed in general practice. This study 
      assessed the opinions and experiences of UK general practitioners (GPs) regarding 
      the management of feline hyperthyroidism. This included an evaluation of 
      preferred treatment modalities and the monitoring of medically treated cats in 
      relation to thyroxine (T4) level, co-morbid disease and adverse drug reactions. 
      Six hundred and three GPs completed an online questionnaire comprising 34 
      questions. Oral medication was the most commonly preferred treatment option 
      (65.7% of respondents), followed by thyroidectomy (27.5%) and then radioiodine 
      (5.5%). When cost of treatment was eliminated as a consideration factor, 
      significantly more respondents selected radioiodine (40.5%, P <0.001). Concerning 
      target total T4 levels during medical management, 48.4% aimed for the lower half 
      of the reference interval (RI), 32.3% anywhere within RI, 13.1% within the top 
      half of RI and 0.5% above the RI; 3.4% evaluated efficacy by physical assessment 
      only. In the presence of chronic kidney disease (CKD) respondents were 
      significantly more likely to target total T4 levels within the upper half of the 
      RI (40.3%) or above it (9.8%) when compared with targets for routine cases (P 
      <0.001). Assessment for unmasking of CKD after initiating treatment or for 
      hypertension was not consistently performed. Variability in monitoring strategies 
      may result in CKD and hypertension remaining undetected, inadequate suppression 
      of T4 levels in cats with concurrent CKD and delayed recognition of potentially 
      significant haematological abnormalities.
CI  - (c) ISFM and AAFP 2014.
FAU - Higgs, Paul
AU  - Higgs P
AD  - School of Veterinary Sciences, University of Bristol, Langford, Bristol, UK 
      paul.higgs@bristol.ac.uk.
FAU - Murray, Jane K
AU  - Murray JK
AD  - School of Veterinary Sciences, University of Bristol, Langford, Bristol, UK.
FAU - Hibbert, Angie
AU  - Hibbert A
AD  - The Feline Centre, Langford Veterinary Services, Langford, Bristol, UK.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140114
PL  - England
TA  - J Feline Med Surg
JT  - Journal of feline medicine and surgery
JID - 100897329
RN  - 0 (Antithyroid Agents)
RN  - 0 (Iodine Radioisotopes)
RN  - Q51BO43MG4 (Thyroxine)
SB  - IM
MH  - Animals
MH  - Antithyroid Agents/adverse effects/therapeutic use
MH  - Cat Diseases/*therapy
MH  - Cats
MH  - *Disease Management
MH  - Hyperthyroidism/complications/therapy/*veterinary
MH  - Iodine Radioisotopes/therapeutic use
MH  - Renal Insufficiency, Chronic/complications/diagnosis/veterinary
MH  - Thyroidectomy/veterinary
MH  - Thyroxine/blood
MH  - Veterinarians/psychology
EDAT- 2014/01/16 06:00
MHDA- 2015/07/02 06:00
CRDT- 2014/01/16 06:00
PHST- 2014/01/16 06:00 [entrez]
PHST- 2014/01/16 06:00 [pubmed]
PHST- 2015/07/02 06:00 [medline]
AID - 1098612X13519633 [pii]
AID - 10.1177/1098612X13519633 [doi]
PST - ppublish
SO  - J Feline Med Surg. 2014 Oct;16(10):788-95. doi: 10.1177/1098612X13519633. Epub 
      2014 Jan 14.