PMID- 24448852
OWN - NLM
STAT- MEDLINE
DCOM- 20141003
LR  - 20140122
IS  - 0717-6163 (Electronic)
IS  - 0034-9887 (Linking)
VI  - 141
IP  - 8
DP  - 2013 Aug
TI  - [Cardiac resynchronization therapy in patients with heart failure: a 10-year 
      experience].
PG  - 968-76
LID - S0034-98872013000800002 [pii]
LID - 10.4067/S0034-98872013000800002 [doi]
AB  - BACKGROUND: Multiple randomized trials support the clinical benefits of cardiac 
      resynchronization therapy (CRT) in patients with heart failure (HF) and 
      ventricular dyssynchrony. Since the year 2000 this therapy has been increasingly 
      used in Chile. AIM: To describe the clinical characteristics and follow-up of HF 
      patients undergoing CRT in a single Chilean university hospital during the last 
      10 years. PATIENTS AND METHODS: All patients undergoing CRT between 2000 and 2010 
      in our university hospital were included. Clinical and echocardiographic data 
      were extracted from medical records and mortality causes were obtained from the 
      National Identification Service. RESULTS: A total of 252 patients underwent CRT 
      during the study period. Seventy five percent were in New York Heart Associatin 
      (NYHA) functional class III and mean ejection fraction was 29 +/- 10%. Complete 
      left bundle branch block was present in 55% and 20% had permanent atrial 
      fibrillation (AF). Mean survival was 86% at 1 year and 82% of patients in NYHA 
      class III-IV improved at least one functional class. Survival was poorer in 
      patients with ischemic etiology (hazard ratio (HR) 1.48), functional class IV (HR 
      2.2), right bundle branch block (RBBB) (HR 3.1) and AF (HR 3.4). No survival 
      differences were observed between patients with and without an implanted 
      cardiodefibrillator. CONCLUSIONS: This series show good clinical outcomes, 
      comparable to those reported in randomized trials. Predictors of worse survival 
      included an ischemic etiology, functional class IV, RBBB and AF. Patients with a 
      defibrillator had no better survival, which could be relevant in countries with 
      limited health care resources.
FAU - Enriquez, Andres
AU  - Enriquez A
FAU - Barrero, Raul
AU  - Barrero R
FAU - Bittner, Alex
AU  - Bittner A
FAU - Frangini, Patricia
AU  - Frangini P
FAU - Baeza, Mariana
AU  - Baeza M
FAU - Millapan, Islandia
AU  - Millapan I
FAU - Gonzalez, Rolando
AU  - Gonzalez R
FAU - Vergara, Ismael
AU  - Vergara I
LA  - spa
PT  - English Abstract
PT  - Journal Article
TT  - Terapia de resincronizacion en pacientes con insuficiencia cardiaca: experiencia 
      acumulada de 10 anos.
PL  - Chile
TA  - Rev Med Chil
JT  - Revista medica de Chile
JID - 0404312
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Bundle-Branch Block/mortality/therapy
MH  - Cardiac Resynchronization Therapy/methods/*mortality/statistics & numerical data
MH  - Chile
MH  - Electrocardiography
MH  - Female
MH  - Heart Failure/*mortality/therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2014/01/23 06:00
MHDA- 2014/10/04 06:00
CRDT- 2014/01/23 06:00
PHST- 2012/10/08 00:00 [received]
PHST- 2013/05/15 00:00 [accepted]
PHST- 2014/01/23 06:00 [entrez]
PHST- 2014/01/23 06:00 [pubmed]
PHST- 2014/10/04 06:00 [medline]
AID - S0034-98872013000800002 [pii]
AID - 10.4067/S0034-98872013000800002 [doi]
PST - ppublish
SO  - Rev Med Chil. 2013 Aug;141(8):968-76. doi: 10.4067/S0034-98872013000800002.