PMID- 24454398 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20140123 LR - 20211021 IS - 1687-9627 (Print) IS - 1687-9635 (Electronic) VI - 2013 DP - 2013 TI - Multifocal Buruli Ulcer Associated with Secondary Infection in HIV Positive Patient. PG - 348628 LID - 10.1155/2013/348628 [doi] LID - 348628 AB - Buruli ulcer is a chronic and infectious skin disease, caused by Mycobacterium ulcerans. It leads to large skin ulceration and sometimes bone infection which is responsible for deformities. Here, we report a case of multifocal form of Buruli ulcer associated with secondary infection in a 46-year-old human immunodeficiency virus (HIV) positive woman. The antimycobacterial drugs combined to surgery allowed curing this multifocal case and rose up two relevant issues: the susceptibility of immune reconstitution inflammatory syndrome (IRIS) occurrence and Mycobacterium dissemination. The deep immune depression, the underline biological, and clinical disorders of the patient might contribute to IRIS occurrence and Buruli ulcer dissemination. Future investigations have to be conducted on the mechanism of IRIS on set and on Mycobacterium ulcerans dissemination after ARV drugs initiation and the patient related underline clinical or biological disorders. FAU - Komenan, Kassi AU - Komenan K AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Elidje, Ecra J AU - Elidje EJ AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Ildevert, Gbery P AU - Ildevert GP AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Yao, Kouassi I AU - Yao KI AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Kanga, Kouame AU - Kanga K AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Kouame, Kouassi A AU - Kouame KA AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Abdoulaye, Sangare AU - Abdoulaye S AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Hamdam, Kourouma S AU - Hamdam KS AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Yao, Yoboue P AU - Yao YP AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. FAU - Jean-Marie, Kanga AU - Jean-Marie K AD - Department of Dermatology and Infectiology, School of Medicine, Felix Houphouet Boigny University of Abidjan, BP 01 V166 Abidjan 01, Cote d'Ivoire. LA - eng PT - Journal Article DEP - 20131225 PL - United States TA - Case Rep Med JT - Case reports in medicine JID - 101512910 PMC - PMC3886605 EDAT- 2014/01/24 06:00 MHDA- 2014/01/24 06:01 PMCR- 2013/12/25 CRDT- 2014/01/24 06:00 PHST- 2013/06/20 00:00 [received] PHST- 2013/12/06 00:00 [revised] PHST- 2013/12/12 00:00 [accepted] PHST- 2014/01/24 06:00 [entrez] PHST- 2014/01/24 06:00 [pubmed] PHST- 2014/01/24 06:01 [medline] PHST- 2013/12/25 00:00 [pmc-release] AID - 10.1155/2013/348628 [doi] PST - ppublish SO - Case Rep Med. 2013;2013:348628. doi: 10.1155/2013/348628. Epub 2013 Dec 25.