PMID- 24455191
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140123
LR  - 20240323
IS  - 2075-8251 (Print)
IS  - 2075-8251 (Linking)
VI  - 5
IP  - 4
DP  - 2013 Oct
TI  - Intensity of Free Radical Processes in Rat Liver under Type 2 Diabetes and 
      Introduction of Epifamin.
PG  - 118-22
AB  - The effect of epifamin on free radical processes, the activity of caspase-1 and 
      -3, aconitate hydratase and citrate content in rat's liver at experimentally 
      induced type 2 diabetes mellitus (T2DM) was studied. The action of epifamin at 
      T2DM leads to a decrease in biochemiluminescence parameters, characterizing the 
      intensity of free radical processes, and changes in aconitase activity and 
      citrate level towards the control. Activities of caspase-1 and caspase-3 in the 
      tissue decreased by a factor of 2.4 and 1.6 in comparison with the levels at the 
      disease. Apparently, epifamin-mediated correction of the level of melatonin, 
      providing a significant antioxidant effect, promotes positive action on the free 
      radical homeostasis.
FAU - Popova, T N
AU  - Popova TN
AD  - Voronezh State University, Universitetskaya pl., 1, Voronezh, Russia, 394006.
FAU - Agarkov, A A
AU  - Agarkov AA
AD  - Voronezh State University, Universitetskaya pl., 1, Voronezh, Russia, 394006.
FAU - Verevkin, A N
AU  - Verevkin AN
AD  - Voronezh State University, Universitetskaya pl., 1, Voronezh, Russia, 394006.
LA  - eng
PT  - Journal Article
PL  - Russia (Federation)
TA  - Acta Naturae
JT  - Acta naturae
JID - 101525823
PMC - PMC3890997
OTO - NOTNLM
OT  - aconitate hydratase
OT  - biochemiluminescence
OT  - citrate, caspase
OT  - epifamin
OT  - type 2 diabetes mellitusXXXX
EDAT- 2014/01/24 06:00
MHDA- 2014/01/24 06:01
PMCR- 2013/10/01
CRDT- 2014/01/24 06:00
PHST- 2014/01/24 06:00 [entrez]
PHST- 2014/01/24 06:00 [pubmed]
PHST- 2014/01/24 06:01 [medline]
PHST- 2013/10/01 00:00 [pmc-release]
PST - ppublish
SO  - Acta Naturae. 2013 Oct;5(4):118-22.