PMID- 24455765
OWN - NLM
STAT- MEDLINE
DCOM- 20140617
LR  - 20190918
IS  - 1879-0372 (Electronic)
IS  - 0952-7915 (Linking)
VI  - 25
IP  - 6
DP  - 2013 Dec
TI  - Dendritic cells in asthma.
PG  - 745-54
AB  - The lungs are constantly exposed to antigens, most of which are non-pathogenic 
      and do not require the induction of an immune response. Dendritic cells (DCs) are 
      situated at the basolateral site of the lungs and continuously scan the 
      environment to detect the presence of pathogens and subsequently initiate an 
      immune response. They are a heterogeneous population of antigen-presenting cells 
      that exert specific functions. Compelling evidence is now provided that DCs are 
      both sufficient and necessary to induce allergic responses against several 
      inhaled harmless allergens. How various DC subsets exactly contribute to the 
      induction of allergic asthma is currently a subject of intense investigation. We 
      here review the current progress in this field.
FAU - van Helden, Mary J
AU  - van Helden MJ
FAU - Lambrecht, Bart N
AU  - Lambrecht BN
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Curr Opin Immunol
JT  - Current opinion in immunology
JID - 8900118
RN  - 0 (Allergens)
SB  - IM
MH  - Allergens/immunology
MH  - Animals
MH  - Asthma/*immunology
MH  - Dendritic Cells/*immunology
MH  - Epithelial Cells/immunology
MH  - Humans
MH  - Lung/immunology
MH  - Th2 Cells/immunology
EDAT- 2014/01/24 06:00
MHDA- 2014/06/18 06:00
CRDT- 2014/01/24 06:00
PHST- 2014/01/24 06:00 [entrez]
PHST- 2014/01/24 06:00 [pubmed]
PHST- 2014/06/18 06:00 [medline]
AID - S0952-7915(13)00179-9 [pii]
AID - 10.1016/j.coi.2013.10.002 [doi]
PST - ppublish
SO  - Curr Opin Immunol. 2013 Dec;25(6):745-54. doi: 10.1016/j.coi.2013.10.002.