PMID- 24459888
OWN - NLM
STAT- MEDLINE
DCOM- 20140220
LR  - 20190923
IS  - 0253-9772 (Print)
IS  - 0253-9772 (Linking)
VI  - 35
IP  - 10
DP  - 2013 Oct
TI  - [The effect of environmental factors and DNA methylation on type 2 diabetes 
      mellitus].
PG  - 1143-52
AB  - Type 2 diabetes mellitus (T2DM) is a glucose metabolic disorder driven by both 
      genetic and environmental factors. Recent DNA methylation studies have 
      established that T2DM may be contributed by environmental factors through the 
      regulation of DNA methylation. Human and animal model studies have made much 
      progress on the interaction between DNA methylation of T2DM genes and 
      environmental factors in multiple tissues. Current studies on DNA methylation of 
      T2DM genes mainly focus on glucose and energy metabolism, inflammation, and so 
      on. This review comprehensively introduces the DNA methylation studies for the 
      genes involved in T2DM and its related environmental factors.
FAU - Tang, Lin-Lin
AU  - Tang LL
AD  - Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo 
      University, Ningbo 315211, China. tll318@163.com
FAU - Liu, Qiong
AU  - Liu Q
AD  - Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo 
      University, Ningbo 315211, China.
FAU - Bu, Shi-Zhong
AU  - Bu SZ
AD  - Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo 
      University, Ningbo 315211, China.
FAU - Xu, Lei-Ting
AU  - Xu LT
AD  - Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo 
      University, Ningbo 315211, China.
FAU - Wang, Qin-Wen
AU  - Wang QW
AD  - Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo 
      University, Ningbo 315211, China.
FAU - Mai, Yi-Feng
AU  - Mai YF
AD  - The Affiliated Hospital, School of Medicine, Ningbo University, Ningbo 315000, 
      China.
FAU - Duan, Shi-Wei
AU  - Duan SW
AD  - Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo 
      University, Ningbo 315211, China.
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - China
TA  - Yi Chuan
JT  - Yi chuan = Hereditas
JID - 9436478
SB  - IM
MH  - Animals
MH  - DNA Methylation
MH  - Diabetes Mellitus, Type 2/*genetics/metabolism
MH  - Epigenesis, Genetic
MH  - *Gene-Environment Interaction
MH  - Humans
EDAT- 2014/01/28 06:00
MHDA- 2014/02/22 06:00
CRDT- 2014/01/28 06:00
PHST- 2014/01/28 06:00 [entrez]
PHST- 2014/01/28 06:00 [pubmed]
PHST- 2014/02/22 06:00 [medline]
AID - 10.3724/sp.j.1005.2013.01143 [doi]
PST - ppublish
SO  - Yi Chuan. 2013 Oct;35(10):1143-52. doi: 10.3724/sp.j.1005.2013.01143.