PMID- 24468423 OWN - NLM STAT- MEDLINE DCOM- 20141014 LR - 20211203 IS - 1478-9523 (Electronic) IS - 1478-9515 (Linking) VI - 12 IP - 1 DP - 2014 Feb TI - Comparing the distress thermometer (DT) with the patient health questionnaire (PHQ)-2 for screening for possible cases of depression among patients newly diagnosed with advanced cancer. PG - 63-8 LID - 10.1017/S1478951513000394 [doi] AB - OBJECTIVE: Distress screening guidelines call for rapid screening for emotional distress at the time of cancer diagnosis. The purpose of this study was to examine the distress thermometer's (DT) ability to screen in patients in treatment for advanced cancer who may be depressed. METHODS: Using cross-sectional data collected from patients within 30 days of diagnosis with advanced cancer, this study used ROC analysis to determine the optimal-cutoff point of the distress thermometer (DT) for screening for depression as measured by the physician health questionnaire (PHQ)-9; inter-test reliability analysis to compare the DT with the PHQ-2 for screening in possible cases of depression, and multivariate analysis to examine associations among the DT emotional problem list (EPL) items with cases of depression. RESULTS: The average age of the 123 patients in the study was 59.9 (12.9) years. Seventy (56.9%) were female. All had Stage 3 or 4 cancers (40% gastrointestinal, 19% gynecologic, 20% head and neck, 21% lung). The mean DT score was 4 (2.7)/10; and 56 (43%) were depressed as measured by the PHQ-9 >/= 5. The optimal DT cut-off score to screen in possible cases of depression was >/= 2/10, with a sensitivity of .96, compared to a sensitivity of .32 of the PHQ-2 >/= 2. Correlation coefficients for the DT >/= 2 and the PHQ-2 with the PHQ-9 >/= 5 were 0.4 and -0.2, respectively. EPL items associated with cases of depression were Depression (OR = 0.15, 0.02-0.85) and Sadness (OR = 0.21, 0.06-0.72). SIGNIFICANCE OF RESULTS: The optimal DT threshold for identifying possible cases of depression at the time of diagnosis is >/= 2; this threshold is more sensitive than the PHQ-2 >/= 2. EPL items may be used with the DT score to triage patients for evaluation. FAU - Lazenby, Mark AU - Lazenby M AD - Yale University School of Nursing, New Haven, Connecticut. FAU - Dixon, Jane AU - Dixon J AD - Yale University School of Nursing, New Haven, Connecticut. FAU - Bai, Mei AU - Bai M AD - Yale University School of Nursing, New Haven, Connecticut. FAU - McCorkle, Ruth AU - McCorkle R AD - Yale University School of Nursing, New Haven, Connecticut. LA - eng GR - R01NR011872/NR/NINR NIH HHS/United States PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural PL - England TA - Palliat Support Care JT - Palliative & supportive care JID - 101232529 SB - IM MH - Adaptation, Psychological MH - Adult MH - Aged MH - Aged, 80 and over MH - Anxiety Disorders/*diagnosis/*nursing/psychology MH - Connecticut MH - Cross-Sectional Studies MH - Depressive Disorder/*diagnosis/*nursing/psychology MH - Female MH - Guideline Adherence MH - *Hospice and Palliative Care Nursing MH - Humans MH - Longitudinal Studies MH - Male MH - Mass Screening/*nursing/*statistics & numerical data MH - Middle Aged MH - Neoplasm Staging MH - Neoplasms/*nursing/pathology/*psychology MH - Nursing Assessment/*statistics & numerical data MH - Psychometrics/statistics & numerical data MH - Reproducibility of Results MH - *Sick Role MH - *Surveys and Questionnaires MH - Translational Research, Biomedical EDAT- 2014/01/29 06:00 MHDA- 2014/10/15 06:00 CRDT- 2014/01/29 06:00 PHST- 2014/01/29 06:00 [entrez] PHST- 2014/01/29 06:00 [pubmed] PHST- 2014/10/15 06:00 [medline] AID - S1478951513000394 [pii] AID - 10.1017/S1478951513000394 [doi] PST - ppublish SO - Palliat Support Care. 2014 Feb;12(1):63-8. doi: 10.1017/S1478951513000394.