PMID- 24470928
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140624
LR  - 20211021
IS  - 2036-7430 (Print)
IS  - 2036-7449 (Electronic)
IS  - 2036-7430 (Linking)
VI  - 4
IP  - 1
DP  - 2012 Jan 2
TI  - Hyperbaric oxygen treatment in three cases of necrotizing infection of the neck.
PG  - e21
LID - 10.4081/idr.2012.e21 [doi]
LID - e21
AB  - Necrotizing infections of the head and neck are rare conditions in our hospital. 
      Clinical and microbiological characteristics of three consecutive cases treated 
      in Haukeland University Hospital in western Norway in the year 2010 are 
      described. Two cases of Lemierre's syndrome and one case with a descending 
      necrotizing mediastinitis (DNM) were diagnosed. All three cases were treated with 
      broad spectrum antibiotics and in two cases surgery was possible. Hyperbaric 
      oxygen treatment (HBOT) with intensive care facilities became recently available 
      at our hospital, and this treatment was used in all these patients regardless of 
      surgery. In one case we describe the use of HBOT on the basis of strong clinical 
      suspicion of anaerobic infection only. Bacterial identification by partial 
      sequencing of the 16SrDNA gene proved to be a useful supplement to conventional 
      culture techniques. All the cases all demonstrated a significant clinical 
      improvement after introduction of HBOT. When HBOT is available, it should be 
      considered as adjunctive treatment in extensive infections with anaerobes.
FAU - Nedrebo, Torbjorn
AU  - Nedrebo T
AD  - Hyperbaric Medical Unit, Dept of Occupational Medicine, Haukeland University 
      Hospital; ; Department of Biomedicine, University of Bergen;
FAU - Bruun, Trond
AU  - Bruun T
AD  - Department of Medicine, Haukeland University Hospital; ; Institute of Medicine, 
      University of Bergen;
FAU - Skjastad, Rune
AU  - Skjastad R
AD  - Department of Microbiology, Haukeland University Hospital;
FAU - Holmaas, Gunhild
AU  - Holmaas G
AD  - Department of Anaesthesia and Intensive Care, Haukeland University Hospital, 
      Norway.
FAU - Skrede, Steinar
AU  - Skrede S
AD  - Department of Medicine, Haukeland University Hospital; ; Institute of Medicine, 
      University of Bergen;
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20120228
PL  - Switzerland
TA  - Infect Dis Rep
JT  - Infectious disease reports
JID - 101537203
PMC - PMC3892647
OTO - NOTNLM
OT  - Lemierre.
OT  - anaerobic
OT  - hyperbaric
OT  - necrotizing
EDAT- 2012/01/02 00:00
MHDA- 2012/01/02 00:01
PMCR- 2012/02/28
CRDT- 2014/01/29 06:00
PHST- 2011/10/19 00:00 [received]
PHST- 2011/12/29 00:00 [revised]
PHST- 2012/01/08 00:00 [accepted]
PHST- 2014/01/29 06:00 [entrez]
PHST- 2012/01/02 00:00 [pubmed]
PHST- 2012/01/02 00:01 [medline]
PHST- 2012/02/28 00:00 [pmc-release]
AID - idr.2012.e21 [pii]
AID - 10.4081/idr.2012.e21 [doi]
PST - epublish
SO  - Infect Dis Rep. 2012 Feb 28;4(1):e21. doi: 10.4081/idr.2012.e21. eCollection 2012 
      Jan 2.