PMID- 24472338
OWN - NLM
STAT- MEDLINE
DCOM- 20141021
LR  - 20190318
IS  - 1876-8784 (Electronic)
IS  - 0028-2162 (Linking)
VI  - 158
IP  - 5
DP  - 2014
TI  - [Peanut allergy, not always the correct diagnosis].
PG  - A6748
AB  - BACKGROUND: Diagnosing peanut allergy in children is complicated. The clinical 
      history can be difficult to interpret, measurement of peanut-specific 
      immunoglobulin E (IgE) is of limited usefulness due to its poor specificity, and 
      the gold standard (double-blind placebo-controlled food challenge) is 
      time-consuming and labour-intensive, limiting its use in daily practice. 
      Under-diagnosing peanut allergy is considered dangerous, because of serious 
      reactions like anaphylaxis. As a result, there is a high probability of 
      over-diagnosis of peanut allergy in the general population, leading to 
      unnecessary peanut-free diets and parental anxiety. CASE DESCRIPTION: We discuss 
      three children diagnosed with peanut allergy, and describe the clinical and 
      diagnostic considerations of peanut allergy. After a detailed history focusing on 
      the reproducibility of objective symptoms after exposure, peanut allergy was 
      excluded in two cases allowing normalization of the diet and reduction of patient 
      and parental anxiety. CONCLUSION: A detailed history, focusing on reproducible 
      and objective symptoms, is helpful in confirmation or exclusion of the diagnosis 
      'peanut allergy' and can thus prevent unnecessary peanut-free diets.
FAU - van Veen, Wilma J
AU  - van Veen WJ
AD  - Amalia Kindcentrum, Isala, Zwolle.
FAU - Brand, Paul L P
AU  - Brand PL
LA  - dut
PT  - Case Reports
PT  - Journal Article
PT  - Review
TT  - Pinda-allergie, niet altijd een terechte diagnose.
PL  - Netherlands
TA  - Ned Tijdschr Geneeskd
JT  - Nederlands tijdschrift voor geneeskunde
JID - 0400770
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/analysis
MH  - Male
MH  - *Medical History Taking
MH  - Peanut Hypersensitivity/*diagnosis/epidemiology
EDAT- 2014/01/30 06:00
MHDA- 2014/10/22 06:00
CRDT- 2014/01/30 06:00
PHST- 2014/01/30 06:00 [entrez]
PHST- 2014/01/30 06:00 [pubmed]
PHST- 2014/10/22 06:00 [medline]
PST - ppublish
SO  - Ned Tijdschr Geneeskd. 2014;158(5):A6748.