PMID- 24473779 OWN - NLM STAT- MEDLINE DCOM- 20140911 LR - 20140129 IS - 1940-6029 (Electronic) IS - 1064-3745 (Linking) VI - 1109 DP - 2014 TI - An overview of HLA typing for hematopoietic stem cell transplantation. PG - 73-85 LID - 10.1007/978-1-4614-9437-9_5 [doi] AB - The selection of a related or an unrelated hematopoietic stem cell donor for a patient requires accurate matching of human leukocyte antigen (HLA) genes in order to maximize the beneficial effects of the transplant. There are various different factors a laboratory must consider in order to achieve an HLA type including the number of samples being processed, level of resolution to be achieved, cost of providing the various tests, and turnaround time required. Each method has its advantages and disadvantages, and in most laboratories, a combination of methods may be used. FAU - Latham, Katy AU - Latham K AD - Anthony Nolan Research Institute, University College London, London, UK. FAU - Little, Ann-Margaret AU - Little AM FAU - Madrigal, J Alejandro AU - Madrigal JA LA - eng PT - Journal Article PT - Review PL - United States TA - Methods Mol Biol JT - Methods in molecular biology (Clifton, N.J.) JID - 9214969 SB - IM MH - *Hematopoietic Stem Cell Transplantation MH - Hematopoietic Stem Cells/*immunology MH - Histocompatibility Testing/*methods MH - Humans MH - Tissue Donors EDAT- 2014/01/30 06:00 MHDA- 2014/09/12 06:00 CRDT- 2014/01/30 06:00 PHST- 2014/01/30 06:00 [entrez] PHST- 2014/01/30 06:00 [pubmed] PHST- 2014/09/12 06:00 [medline] AID - 10.1007/978-1-4614-9437-9_5 [doi] PST - ppublish SO - Methods Mol Biol. 2014;1109:73-85. doi: 10.1007/978-1-4614-9437-9_5.