PMID- 24477054
OWN - NLM
STAT- MEDLINE
DCOM- 20141017
LR  - 20220321
IS  - 1528-1159 (Electronic)
IS  - 0362-2436 (Linking)
VI  - 38
IP  - 9
DP  - 2013 Apr 20
TI  - What is the effect of surgery on the quality of life of the adolescent with 
      adolescent idiopathic scoliosis? A review and statistical analysis of the 
      literature.
PG  - 786-94
LID - 10.1097/BRS.0b013e3182837c95 [doi]
AB  - STUDY DESIGN: Review and statistical analysis of studies evaluating the effect of 
      surgery on the health-related quality of life of adolescents with adolescent 
      idiopathic scoliosis, using Scoliosis Research Society (SRS) outcomes. OBJECTIVE: 
      Apply published minimum clinical important differences (MCID) values for the 
      SRS22r questionnaire to the literature to identify what areas of health-related 
      quality of life are consistently affected by surgery and whether changes are 
      clinically meaningful. SUMMARY OF BACKGROUND DATA: The interpretation of 
      published studies using the SRS outcomes has been limited by the lack of MCID 
      values for the questionnaire domains. The recent publication of these data allows 
      the clinical importance of any changes in these studies to be examined for the 
      first time. METHODS: A literature search was undertaken to locate suitable 
      studies that were then analyzed. Statistically significant differences from 
      baseline to 2 years postoperatively were ascertained by narratively reporting the 
      analyses within included studies. When possible, clinically significant changes 
      were assessed using 95% confidence intervals for the change in mean domain score. 
      If the lower bound of the confidence intervals for the change exceeded the MCID 
      for that domain, the change was considered clinically significant. RESULTS: The 
      numbers of cohorts available for the different analyses varied (5-16). Eighty-one 
      percent and 94% of included cohorts experienced statistically significant 
      improvements in pain and self-image domains. In terms of clinical significance, 
      it was only self-image that regularly improved by more than MCID, doing so in 4 
      of 5 included cohorts (80%) compared with 1 of 12 cohorts (8%) for pain. No 
      clinically relevant changes occurred in mental health or activity domains. 
      CONCLUSION: Evidence suggests that surgery can lead to clinically important 
      improvement in patient self-image. Surgeons and patients should be aware of the 
      limited evidence for improvements in domains other than self-image after surgery. 
      Surgical decision-making will also be influenced by the natural history of 
      adolescent idiopathic scoliosis.
FAU - Rushton, Paul R P
AU  - Rushton PR
AD  - From the Centre for Spinal Studies and Surgery, Queen's Medical Centre, 
      Nottingham, United Kingdom.
FAU - Grevitt, Michael P
AU  - Grevitt MP
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Spine (Phila Pa 1976)
JT  - Spine
JID - 7610646
SB  - IM
MH  - Adolescent
MH  - Cohort Studies
MH  - Humans
MH  - Multicenter Studies as Topic/psychology/statistics & numerical data
MH  - Pain Measurement/*psychology/*statistics & numerical data
MH  - Quality of Life/*psychology
MH  - Scoliosis/epidemiology/*psychology/*surgery
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2014/01/31 06:00
MHDA- 2014/10/18 06:00
CRDT- 2014/01/31 06:00
PHST- 2014/01/31 06:00 [entrez]
PHST- 2014/01/31 06:00 [pubmed]
PHST- 2014/10/18 06:00 [medline]
AID - 00007632-201304200-00013 [pii]
AID - 10.1097/BRS.0b013e3182837c95 [doi]
PST - ppublish
SO  - Spine (Phila Pa 1976). 2013 Apr 20;38(9):786-94. doi: 
      10.1097/BRS.0b013e3182837c95.