PMID- 24484860
OWN - NLM
STAT- MEDLINE
DCOM- 20140327
LR  - 20140528
IS  - 1879-1913 (Electronic)
IS  - 0002-9149 (Linking)
VI  - 113
IP  - 4
DP  - 2014 Feb 15
TI  - Relation of ST-segment elevation before and after percutaneous transluminal 
      coronary angioplasty to left ventricular area at risk, myocardial infarct size, 
      and systolic function.
PG  - 593-600
LID - S0002-9149(13)02252-2 [pii]
LID - 10.1016/j.amjcard.2013.11.007 [doi]
AB  - Electrocardiography is an excellent tool for decision making in patients with ST 
      elevation myocardial infarction (STEMI). However, little is known on the 
      correlation between its dynamic changes during primary percutaneous coronary 
      intervention (PCI) and the anatomic information provided by cardiovascular 
      magnetic resonance. The study aimed to assess the predictive value of dynamic 
      ST-segment changes before and after PCI on myocardial area at risk (AAR), infarct 
      size, and left ventricular function in patients with STEMI. Eighty-five 
      consecutive patients with a first STEMI were included. An electrocardiogram was 
      recorded before and after PCI at 1, 24, 48, 72, and 120 hours. Sum of ST 
      elevation (sumSTE), the number of STE, and STE resolution (resSTE) were 
      determined. Complete resSTE was defined as >/=70% resolution, and patients were 
      classified into 3 groups: group 1 (resSTE 1 hour after PCI) n = 39; group 2 
      (resSTE 120 hour after PCI) n = 27; and group 3, without resSTE (n = 19). 
      Cardiovascular magnetic resonance was performed during hospitalization and at 6 
      months. Left ventricular volumes, ejection fraction, AAR, infarct size, 
      myocardial salvage index, and microvascular obstruction were determined. Before 
      PCI, the number of STE and sumSTE were best associated with AAR (p <0.001). After 
      PCI, lack of resSTE (group 3) was associated with larger infarct size, MVO, and 
      lower myocardial salvage index. However, sumSTE at 120 hours after PCI best 
      discriminated patients with larger infarct size, ventricular volumes, and lower 
      ejection fraction during hospitalization and at follow-up. In conclusion, 
      admission sumSTE best correlates with AAR, whereas sumSTE at 120 hours rather 
      than early resSTE best correlates with infarct size and left ventricular volumes 
      during hospitalization and at 6 months.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Rodriguez-Palomares, Jose F
AU  - Rodriguez-Palomares JF
AD  - Department of Cardiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain. 
      Electronic address: jfrodrig@vhebron.net.
FAU - Figueras-Bellot, Jaume
AU  - Figueras-Bellot J
AD  - Department of Cardiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Descalzo, Martin
AU  - Descalzo M
AD  - Department of Cardiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Moral, Sergio
AU  - Moral S
FAU - Otaegui, Imanol
AU  - Otaegui I
AD  - Department of Cardiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Pineda, Victor
AU  - Pineda V
AD  - Department of Radiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Del Blanco, Bruno Garcia
AU  - Del Blanco BG
AD  - Department of Cardiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Gonzalez-Alujas, Maria T
AU  - Gonzalez-Alujas MT
AD  - Department of Cardiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Evangelista Masip, Artur
AU  - Evangelista Masip A
AD  - Department of Cardiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Garcia-Dorado, David
AU  - Garcia-Dorado D
AD  - Department of Cardiology, Hospital Universitari Vall d'Hebron, Vall Hebron 
      Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
LA  - eng
PT  - Journal Article
DEP - 20131123
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
SB  - IM
EIN - Am J Cardiol. 2014 Apr 15;113(8):1448. Moral, Sergi [corrected to Moral, Sergio]
MH  - Aged
MH  - Coronary Vessels/*pathology
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Linear Models
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis/physiopathology/*surgery
MH  - Percutaneous Coronary Intervention/*methods
MH  - Prospective Studies
MH  - Systole
MH  - Treatment Outcome
MH  - Ventricular Dysfunction, Left/*diagnosis/physiopathology
MH  - Ventricular Function, Left/physiology
EDAT- 2014/02/04 06:00
MHDA- 2014/03/29 06:00
CRDT- 2014/02/04 06:00
PHST- 2013/09/04 00:00 [received]
PHST- 2013/11/05 00:00 [revised]
PHST- 2013/11/05 00:00 [accepted]
PHST- 2014/02/04 06:00 [entrez]
PHST- 2014/02/04 06:00 [pubmed]
PHST- 2014/03/29 06:00 [medline]
AID - S0002-9149(13)02252-2 [pii]
AID - 10.1016/j.amjcard.2013.11.007 [doi]
PST - ppublish
SO  - Am J Cardiol. 2014 Feb 15;113(4):593-600. doi: 10.1016/j.amjcard.2013.11.007. 
      Epub 2013 Nov 23.