PMID- 24491116
OWN - NLM
STAT- MEDLINE
DCOM- 20140929
LR  - 20240325
IS  - 1469-8137 (Electronic)
IS  - 0028-646X (Print)
IS  - 0028-646X (Linking)
VI  - 201
IP  - 4
DP  - 2014 Mar
TI  - RuBPCase activase (RCA) mediates growth-defense trade-offs: silencing RCA 
      redirects jasmonic acid (JA) flux from JA-isoleucine to methyl jasmonate (MeJA) 
      to attenuate induced defense responses in Nicotiana attenuata.
PG  - 1385-1395
LID - 10.1111/nph.12591 [doi]
AB  - * RuBPCase activase (RCA), an abundant photosynthetic protein, is strongly 
      down-regulated in response to Manduca sexta's oral secretion (OS) in Nicotiana 
      attenuata. RCA-silenced plants are impaired not only in photosynthetic capacity 
      and growth, but also in jasmonic acid-isoleucine (JA-Ile) signaling, and 
      herbivore resistance mediated by JA-Ile-dependent defense traits. These responses 
      are consistent with a resource-based growth-defense trade-off. * As JA + Ile 
      supplementation of OS restored wild-type (WT) levels of JA-Ile, defenses and 
      resistance to M. sexta, but OS supplemented individually with JA or Ile did not, 
      the JA-Ile deficiency of RCA-silenced plants could not be attributed to lower JA 
      or Ile pools or JAR4/6 conjugating activity. Similar levels of JA-Ile derivatives 
      after OS elicitation indicated unaltered JA-Ile turnover, and lower levels of 
      other JA conjugates ruled out competition from other conjugation reactions. * 
      RCA-silenced plants accumulated more methyl jasmonate (MeJA) after OS 
      elicitation, which corresponded to increased jasmonate methyltransferase (JMT) 
      activity. RCA silencing phenocopies JMT overexpression, wherein elevated JMT 
      activity redirects OS-elicited JA flux towards inactive MeJA, creating a JA sink 
      which depletes JA-Ile and its associated defense responses. * Hence, RCA plays an 
      additional non-photosynthetic role in attenuating JA-mediated defenses and their 
      associated costs, potentially allowing plants to anticipate resource-based 
      constraints on growth before they actually occur.
CI  - (c) 2013 Max Planck Society. New Phytologist (c) 2013 New Phytologist Trust.
FAU - Mitra, Sirsha
AU  - Mitra S
AD  - Department of Molecular Ecology, Max Planck Institute for Chemical Ecology, 
      Hans-Knoll-Strasse 8, 07745, Jena, Germany.
FAU - Baldwin, Ian T
AU  - Baldwin IT
AD  - Department of Molecular Ecology, Max Planck Institute for Chemical Ecology, 
      Hans-Knoll-Strasse 8, 07745, Jena, Germany.
LA  - eng
GR  - 293926/ERC_/European Research Council/International
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131111
PL  - England
TA  - New Phytol
JT  - The New phytologist
JID - 9882884
RN  - 0 (Acetates)
RN  - 0 (Cyclopentanes)
RN  - 0 (Oxylipins)
RN  - 0 (Plant Proteins)
RN  - 0 (rca protein, plant)
RN  - 04Y7590D77 (Isoleucine)
RN  - 6RI5N05OWW (jasmonic acid)
RN  - 900N171A0F (methyl jasmonate)
RN  - EC 2.1.1.- (Methyltransferases)
SB  - IM
MH  - Acetates/*metabolism
MH  - Animals
MH  - Cyclopentanes/*metabolism/pharmacology
MH  - *Gene Silencing/drug effects
MH  - Herbivory/drug effects
MH  - Isoleucine/*metabolism
MH  - Manduca/drug effects/physiology
MH  - Methylation
MH  - Methyltransferases/metabolism
MH  - Oxylipins/*metabolism/pharmacology
MH  - Plant Proteins/*metabolism
MH  - Signal Transduction/drug effects
MH  - Nicotiana/drug effects/enzymology/*growth & development/*immunology
PMC - PMC4996320
MID - EMS57841
OID - NLM: EMS57841
OTO - NOTNLM
OT  - Manduca sexta
OT  - Nicotiana attenuata
OT  - RuBPCase activase
OT  - herbivory
OT  - jasmonate methyl transferase
OT  - jasmonate signaling
OT  - methyl jasmonate
OT  - plant defense
EDAT- 2014/02/05 06:00
MHDA- 2014/09/30 06:00
PMCR- 2016/08/24
CRDT- 2014/02/05 06:00
PHST- 2013/09/06 00:00 [received]
PHST- 2013/10/03 00:00 [accepted]
PHST- 2014/02/05 06:00 [entrez]
PHST- 2014/02/05 06:00 [pubmed]
PHST- 2014/09/30 06:00 [medline]
PHST- 2016/08/24 00:00 [pmc-release]
AID - 10.1111/nph.12591 [doi]
PST - ppublish
SO  - New Phytol. 2014 Mar;201(4):1385-1395. doi: 10.1111/nph.12591. Epub 2013 Nov 11.