PMID- 24505639
OWN - NLM
STAT- MEDLINE
DCOM- 20140311
LR  - 20140207
IS  - 0324-0959 (Print)
IS  - 0324-0959 (Linking)
VI  - 52
IP  - 7
DP  - 2013
TI  - [Gastroesophageal reflux disease in pregnancy].
PG  - 35-40
AB  - The incidence of GERD is high during pregnancy. Hormonal and mechanical factors 
      in pregnancy alter the structure and function of the normal physiological 
      barriers to reflux of gastric contents into the oesophagus. Most of the patient 
      benefit from lifestyle changes, but require pharmacological treatment for full 
      alleviation of their symptoms. Collaboration between obstetricians and 
      gastroenterologists is recommended, with primary focus on the safety of the 
      mother, fetus and neonate. It is recommended to initiate treatment with lifestyle 
      changes and antacids. As a second line histamine-2 receptor antagonists (H2RA) 
      and proton pump inhibitors (PPI) are tried. Careful discussion of the risks and 
      benefits of the therapy with the patient should precede treatment with any of 
      these medications. In patients with no history of GERD, the symptoms usually 
      resolve after delivery.
FAU - Nikolov, A
AU  - Nikolov A
FAU - Pevtichev, S
AU  - Pevtichev S
FAU - Petrova, D
AU  - Petrova D
LA  - bul
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Bulgaria
TA  - Akush Ginekol (Sofiia)
JT  - Akusherstvo i ginekologiia
JID - 0370455
RN  - 0 (Antacids)
RN  - 0 (Histamine H2 Antagonists)
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Antacids/therapeutic use
MH  - Female
MH  - Gastroesophageal Reflux/complications/*diagnosis/*drug therapy
MH  - Histamine H2 Antagonists/therapeutic use
MH  - Humans
MH  - Pregnancy
MH  - Pregnancy Complications/*diagnosis/*drug therapy
MH  - Proton Pump Inhibitors/therapeutic use
EDAT- 2014/02/08 06:00
MHDA- 2014/03/13 06:00
CRDT- 2014/02/08 06:00
PHST- 2014/02/08 06:00 [entrez]
PHST- 2014/02/08 06:00 [pubmed]
PHST- 2014/03/13 06:00 [medline]
PST - ppublish
SO  - Akush Ginekol (Sofiia). 2013;52(7):35-40.