PMID- 24510571
OWN - NLM
STAT- MEDLINE
DCOM- 20140327
LR  - 20221207
IS  - 1003-9406 (Print)
IS  - 1003-9406 (Linking)
VI  - 31
IP  - 1
DP  - 2014 Feb
TI  - [A novel human leukocyte antigen-A*33:44 allele revealed by sequence analysis].
PG  - 85-7
LID - 10.3760/cma.j.issn.1003-9406.2014.01.020 [doi]
AB  - OBJECTIVE: To analyze the sequence of a novel human leukocyte antigen 
      (HLA)-A*33:44 allele. METHODS: A novel HLA-A allele was found by double-stranded 
      sequencing combined with single-stranded sequencing. The frequency of the novel 
      allele was determined by population survey. RESULTS: Genomic sequence of this 
      novel HLA-A*33:44 allele (accession No. HQ873871) has differed from 
      HLA-B*33:03:01 by one nucleotide in exon 4, which resulted in nt 866 G--> A 
      substitution, which results in an amino acid substitution from Gly(GGT) to 
      Asp(GAT) at codon 265. This alternation is a new single nucleotide polymorphism 
      compared with other HLA-A alleles. The frequency of this new allele is less than 
      0.0003 in Chinese Han population. CONCLUSION: A mutation has been found in exon 4 
      of the novel HLA-A*33:44 allele, which may provide more information for HLA gene 
      study.
FAU - Ding, Haoqiang
AU  - Ding H
AD  - Institute of Blood Transfusion, Guangzhou Blood Center, Guangzhou, Guangdong 
      510095, P.R.China. 779684055@qq.com.
FAU - Ye, Xin
AU  - Ye X
FAU - Huang, Yingfeng
AU  - Huang Y
FAU - Shao, Yuan
AU  - Shao Y
FAU - Chen, Yangkai
AU  - Chen Y
FAU - Xia, Wenjie
AU  - Xia W
FAU - Xiong, Baiyu
AU  - Xiong B
LA  - chi
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi
JT  - Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese 
      journal of medical genetics
JID - 9425197
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-A*33 antigen)
SB  - IM
MH  - Adult
MH  - Alleles
MH  - Amino Acid Substitution
MH  - Asian People/*genetics
MH  - Female
MH  - HLA-A Antigens/*genetics
MH  - Humans
MH  - Male
MH  - Polymorphism, Single Nucleotide
MH  - Sequence Analysis, DNA/methods
EDAT- 2014/02/11 06:00
MHDA- 2014/03/29 06:00
CRDT- 2014/02/11 06:00
PHST- 2014/02/11 06:00 [entrez]
PHST- 2014/02/11 06:00 [pubmed]
PHST- 2014/03/29 06:00 [medline]
AID - 940631020 [pii]
AID - 10.3760/cma.j.issn.1003-9406.2014.01.020 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2014 Feb;31(1):85-7. doi: 
      10.3760/cma.j.issn.1003-9406.2014.01.020.