PMID- 24512759 OWN - NLM STAT- MEDLINE DCOM- 20140903 LR - 20171116 IS - 2325-8179 (Electronic) IS - 2325-8160 (Linking) VI - 45 Online DP - 2014 Feb 14 TI - Bilateral choroidal excavation in best vitelliform macular dystrophy. PG - e8-e10 LID - 10.3928/23258160-20140205-01 [doi] AB - Focal choroidal excavation (FCE) has recently been described as one or more localized areas of choroidal excavation on spectral-domain optical coherence tomography (SD-OCT). The authors describe a case of bilateral FCE in Best vitelliform macular dystrophy (VMD). SD-OCT revealed FCE in both eyes characterized by interruption of the internal segment-outer segment junction and the presence of subretinal hyporeflective space. This is the first report describing bilateral FCE in a distinct macular disorder and specifically with VMD. Future investigations are warranted to ascertain the involvement of other macular dystrophies with atrophic evolution and the impact of FCE on the clinical course. [Ophthalmic Surg Lasers Imaging Retina. 2014;45:e8-e10.]. CI - Copyright 2014, SLACK Incorporated. FAU - Parodi, Maurizio Battaglia AU - Parodi MB FAU - Zucchiatti, Ilaria AU - Zucchiatti I FAU - Fasce, Francesco AU - Fasce F FAU - Bandello, Francesco AU - Bandello F LA - eng PT - Case Reports PT - Journal Article DEP - 20140214 PL - United States TA - Ophthalmic Surg Lasers Imaging Retina JT - Ophthalmic surgery, lasers & imaging retina JID - 101599215 RN - 0 (BEST1 protein, human) RN - 0 (Bestrophins) RN - 0 (Chloride Channels) RN - 0 (Eye Proteins) RN - 0 (RNA, Messenger) SB - IM MH - Bestrophins MH - Chloride Channels/genetics MH - Choroid Diseases/*diagnosis MH - Electrooculography MH - Eye Proteins/genetics MH - Fluorescein Angiography MH - Humans MH - Male MH - Middle Aged MH - Polymerase Chain Reaction MH - RNA, Messenger/analysis MH - Retinal Photoreceptor Cell Inner Segment/pathology MH - Retinal Photoreceptor Cell Outer Segment/pathology MH - Retinal Pigment Epithelium/pathology MH - Tomography, Optical Coherence MH - Vision Disorders/diagnosis MH - Visual Acuity MH - Vitelliform Macular Dystrophy/*diagnosis/genetics EDAT- 2014/02/12 06:00 MHDA- 2014/09/04 06:00 CRDT- 2014/02/12 06:00 PHST- 2013/06/14 00:00 [received] PHST- 2013/11/05 00:00 [accepted] PHST- 2014/02/12 06:00 [entrez] PHST- 2014/02/12 06:00 [pubmed] PHST- 2014/09/04 06:00 [medline] AID - 10.3928/23258160-20140205-01 [doi] PST - epublish SO - Ophthalmic Surg Lasers Imaging Retina. 2014 Feb 14;45 Online:e8-e10. doi: 10.3928/23258160-20140205-01.