PMID- 24522793
OWN - NLM
STAT- MEDLINE
DCOM- 20150209
LR  - 20211021
IS  - 1573-5168 (Electronic)
IS  - 0920-1742 (Linking)
VI  - 40
IP  - 4
DP  - 2014 Aug
TI  - The stimulatory effect of LED light spectra on genes related to photoreceptors 
      and skin pigmentation in goldfish (Carassius auratus).
PG  - 1229-38
LID - 10.1007/s10695-014-9918-7 [doi]
AB  - This study aimed to assess differences in genes related to skin color of goldfish 
      (Carassius auratus) exposed to light-emitting diodes (LEDs): red, green, and 
      purple. We investigated differences in the expression of mammalian-like 
      melanopsin (Opn4m), rhodopsin (RH), melanin-concentrating hormone (MCH), 
      melanin-concentrating hormone receptor (MCH-R), and proopiomelanocortin (POMC) in 
      goldfish exposed to different LED light spectra. Opn4m, RH, MCH, and MCH-R mRNA 
      levels were significantly higher in the green and purple LED groups than in the 
      white fluorescent bulb (control) and red LED groups. Furthermore, skin cells were 
      isolated to measure the MCH-R mRNA expression levels. The results show that the 
      mRNA expression levels were significantly higher in the green and purple LED 
      groups than in the control and red LED groups. In addition, body weights in the 
      green and purple LED groups were significantly higher than those in the control 
      and red LED groups. However, POMC mRNA expression levels in the green and purple 
      LED groups were significantly lower than those in the control and red LED groups. 
      These results suggest that specific wavelengths regulate fish skin color through 
      neuropeptide hormones and photoreceptors, and POMC, which is related to stress 
      hormones and melatonin, is associated with stress levels as well as skin color.
FAU - Shin, Hyun Suk
AU  - Shin HS
AD  - Division of Marine Environment and BioScience, Korea Maritime and Ocean 
      University, Busan, 606-791, Republic of Korea.
FAU - Choi, Cheol Young
AU  - Choi CY
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140213
PL  - Netherlands
TA  - Fish Physiol Biochem
JT  - Fish physiology and biochemistry
JID - 100955049
RN  - 0 (DNA Primers)
SB  - IM
MH  - Analysis of Variance
MH  - Animals
MH  - *Color
MH  - DNA Primers/genetics
MH  - Gene Expression Regulation/*physiology/radiation effects
MH  - Goldfish/*genetics/physiology
MH  - *Light
MH  - Photoreceptor Cells, Vertebrate/*metabolism
MH  - Real-Time Polymerase Chain Reaction
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Skin Pigmentation/*genetics
EDAT- 2014/02/14 06:00
MHDA- 2015/02/11 06:00
CRDT- 2014/02/14 06:00
PHST- 2013/09/04 00:00 [received]
PHST- 2014/02/03 00:00 [accepted]
PHST- 2014/02/14 06:00 [entrez]
PHST- 2014/02/14 06:00 [pubmed]
PHST- 2015/02/11 06:00 [medline]
AID - 10.1007/s10695-014-9918-7 [doi]
PST - ppublish
SO  - Fish Physiol Biochem. 2014 Aug;40(4):1229-38. doi: 10.1007/s10695-014-9918-7. 
      Epub 2014 Feb 13.