PMID- 24527043
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140303
LR  - 20211021
IS  - 1741-427X (Print)
IS  - 1741-4288 (Electronic)
IS  - 1741-427X (Linking)
VI  - 2014
DP  - 2014
TI  - Effectiveness, medication patterns, and adverse events of traditional chinese 
      herbal patches for osteoarthritis: a systematic review.
PG  - 343176
LID - 10.1155/2014/343176 [doi]
LID - 343176
AB  - Objective. The aim of this study is to systematically evaluate the evidence 
      whether traditional Chinese herbal patches (TCHPs) for osteoarthritis (OA) are 
      effective and safe and analyze their medication patterns. Methods. A systematic 
      literature search was performed using all the possible Medical Subject Headings 
      (MeSH) and keywords from January 1979 to July 2013. Both randomized controlled 
      trials (RCTs) and observational studies were included. Estimated effects were 
      analyzed using mean difference (MD) or relative risk (RR) with 95% confidence 
      intervals (CI) and meta-analysis. Results. 86 kinds of TCHPs were identified. 
      RCTs and controlled clinical trials (CCTs) which were mostly of low quality 
      favored TCHPs for local pain and dysfunction relief. TCHPs, compared with 
      diclofenac ointment, had significant effects on global effectiveness rate (RR = 
      0.50; 95% CI (0.29, 0.87)). Components of formulae were mainly based on the 
      compounds "Xiao Huo Luo Dan" (Minor collateral-freeing pill) and "Du Huo Ji Sheng 
      Tang" (Angelicae Pubescentis and Loranthi decoction). Ten kinds of adverse events 
      (AEs), mainly consisting of itching and/or local skin rashes, were identified 
      after 3-4 weeks of follow-up. Conclusions. TCHPs have certain evidence in 
      improving global effectiveness rate for OA; however, more rigorous studies are 
      warranted to support their use.
FAU - Wang, Xuezong
AU  - Wang X
AD  - Shi's Center of Orthopedics and Traumatology, Shuguang Hospital, Shanghai 
      University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, 
      Shanghai 201203, China.
FAU - Wei, Songpu
AU  - Wei S
AUID- ORCID: 0000-0002-2182-221X
AD  - Institute of Traumatology & Orthopedics, Shanghai Academy of Traditional Chinese 
      Medicine, Shanghai 201203, China.
FAU - Liu, Ting
AU  - Liu T
AD  - Shi's Center of Orthopedics and Traumatology, Shuguang Hospital, Shanghai 
      University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, 
      Shanghai 201203, China.
FAU - Pang, Jian
AU  - Pang J
AUID- ORCID: 0000-0003-0167-8553
AD  - Institute of Traumatology & Orthopedics, Shanghai Academy of Traditional Chinese 
      Medicine, Shanghai 201203, China.
FAU - Gao, Ningyang
AU  - Gao N
AD  - Shi's Center of Orthopedics and Traumatology, Shuguang Hospital, Shanghai 
      University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, 
      Shanghai 201203, China.
FAU - Ding, Daofang
AU  - Ding D
AD  - Institute of Traumatology & Orthopedics, Shanghai Academy of Traditional Chinese 
      Medicine, Shanghai 201203, China.
FAU - Duan, Tieli
AU  - Duan T
AD  - Institute of Traumatology & Orthopedics, Shanghai Academy of Traditional Chinese 
      Medicine, Shanghai 201203, China.
FAU - Cao, Yuelong
AU  - Cao Y
AD  - Shi's Center of Orthopedics and Traumatology, Shuguang Hospital, Shanghai 
      University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, 
      Shanghai 201203, China ; Institute of Traumatology & Orthopedics, Shanghai 
      Academy of Traditional Chinese Medicine, Shanghai 201203, China.
FAU - Zheng, Yuxin
AU  - Zheng Y
AD  - Shi's Center of Orthopedics and Traumatology, Shuguang Hospital, Shanghai 
      University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, 
      Shanghai 201203, China.
FAU - Zhan, Hongsheng
AU  - Zhan H
AUID- ORCID: 0000-0002-7444-7185
AD  - Shi's Center of Orthopedics and Traumatology, Shuguang Hospital, Shanghai 
      University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, 
      Shanghai 201203, China.
LA  - eng
PT  - Journal Article
DEP - 20140114
PL  - United States
TA  - Evid Based Complement Alternat Med
JT  - Evidence-based complementary and alternative medicine : eCAM
JID - 101215021
PMC - PMC3914464
EDAT- 2014/02/15 06:00
MHDA- 2014/02/15 06:01
PMCR- 2014/01/14
CRDT- 2014/02/15 06:00
PHST- 2013/06/05 00:00 [received]
PHST- 2013/08/17 00:00 [revised]
PHST- 2013/08/18 00:00 [accepted]
PHST- 2014/02/15 06:00 [entrez]
PHST- 2014/02/15 06:00 [pubmed]
PHST- 2014/02/15 06:01 [medline]
PHST- 2014/01/14 00:00 [pmc-release]
AID - 10.1155/2014/343176 [doi]
PST - ppublish
SO  - Evid Based Complement Alternat Med. 2014;2014:343176. doi: 10.1155/2014/343176. 
      Epub 2014 Jan 14.