PMID- 24527605
OWN - NLM
STAT- MEDLINE
DCOM- 20150908
LR  - 20181202
IS  - 1672-173X (Print)
IS  - 1672-173X (Linking)
VI  - 45
IP  - 1
DP  - 2014 Jan
TI  - [The clinical significance of preoperative enteral immune nutrition in patients 
      with malignant gastrointestinal tumors].
PG  - 167-70
AB  - OBJECTIVE: To study the impact of preoperative enteral immune nutrition on 
      patients with malignant gastrointestinal tumors. METHODS: 82 patients with 
      malignant gastrointestinal tumors were divided equally into 2 groups:enteral 
      nutrition group (EN) and normal diet group (Control). Enteral Nutritional 
      Emulsion (TPF-T) served as nasogastically-fed liquid diet for the patients in EN 
      group over a period of 7 days prior to surgery. Normal diet was given to the 
      patients in control group under the same condition as those in EN group in terms 
      of calories and nitrogen contents. Enzyme linked immunosorbent assay (ELISA) was 
      performed to determine the quantity of serum albumin (ALB), transferrin protein 
      (TRF), pre-albumin (PA) and retinol binding protein (RBP). Flow cytometry (FCM) 
      was performed to determine T cell subsets. Postoperative complications, 
      resumption of peristalsis, length of hospital stay, and nutritional costs were 
      also recorded. RESULTS: TRF, PA and RBP increased significantly in the patients 
      in EN group compared with those in control group (P < 0.05). The patients in EN 
      group had significantly higher proportions of CD3+, CD4+/CD8+ higher than those 
      of control (P < 0.05). No serious complications (eg. death or gastrointestinal 
      fistula) were found in the patients. The total nutritional cost for the patients 
      in EN group was similar to that of the controls (P > 0.05). The patients in EN 
      group had less postoperative complications, quicker resumption of peristalsis, 
      shorter hospital stay and lower level of postoperative nutrition cost compared 
      with those of controls (P < 0.05). CONCLUSION: Enteral nutrition support can 
      improve the nutritional status and immunity of patients with malignant 
      gastrointestinal tumors, which has both pre-operative and post-operative benefits 
      for the patients.
FAU - Huang, Zheng-Jie
AU  - Huang ZJ
AD  - Department of Surgical Oncology, the First Affiliated Hospital of Xiamen 
      University, Xiamen 361003, China.
FAU - Chen, Bai-Sheng
AU  - Chen BS
AD  - The First Clinical Medical College, Fujian Medical University, Fuzhou 350004, 
      China.
FAU - You, Jun
AU  - You J
AD  - Department of Surgical Oncology, the First Affiliated Hospital of Xiamen 
      University, Xiamen 361003, China.
FAU - Wu, Bing-Lin
AU  - Wu BL
AD  - The First Clinical Medical College, Fujian Medical University, Fuzhou 350004, 
      China.
FAU - Jiang, Long
AU  - Jiang L
AD  - The First Clinical Medical College, Fujian Medical University, Fuzhou 350004, 
      China.
FAU - Feng, Qing-Zhao
AU  - Feng QZ
AD  - Department of Surgical Oncology, the First Affiliated Hospital of Xiamen 
      University, Xiamen 361003, China.
FAU - Luo, Qi
AU  - Luo Q
AD  - Department of Surgical Oncology, the First Affiliated Hospital of Xiamen 
      University, Xiamen 361003, China.
LA  - chi
PT  - Controlled Clinical Trial
PT  - Journal Article
PL  - China
TA  - Sichuan Da Xue Xue Bao Yi Xue Ban
JT  - Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical 
      science edition
JID - 101162609
RN  - 0 (Retinol-Binding Proteins)
RN  - 0 (Serum Albumin)
RN  - 0 (Transferrin)
SB  - IM
MH  - *Enteral Nutrition
MH  - Gastrointestinal Neoplasms/*therapy
MH  - Humans
MH  - Length of Stay
MH  - Nutritional Status
MH  - Postoperative Complications
MH  - *Preoperative Care
MH  - Retinol-Binding Proteins
MH  - Serum Albumin
MH  - T-Lymphocyte Subsets
MH  - Transferrin
EDAT- 2014/02/18 06:00
MHDA- 2015/09/09 06:00
CRDT- 2014/02/18 06:00
PHST- 2014/02/18 06:00 [entrez]
PHST- 2014/02/18 06:00 [pubmed]
PHST- 2015/09/09 06:00 [medline]
PST - ppublish
SO  - Sichuan Da Xue Xue Bao Yi Xue Ban. 2014 Jan;45(1):167-70.