PMID- 24528017
OWN - NLM
STAT- MEDLINE
DCOM- 20141112
LR  - 20190606
IS  - 2476-762X (Electronic)
IS  - 1513-7368 (Linking)
VI  - 15
IP  - 1
DP  - 2014
TI  - Lung cancer in women: a single institution experience with 50 patients.
PG  - 151-4
AB  - BACKGROUND: Lung cancer is the most common cause of cancer-related death 
      worldwide. The incidence of lung cancer is aproximately 7-8 thousand percent in 
      Turkish women. In this study, we aimed to evaluate the clinical, pathological 
      properties and survival data of female patients with lung cancer who were treated 
      in our center. MATERIALS AND METHODS: From 2007 to 2012, 50 women with lung 
      cancer were enrolled. Patient data were evaluated retrospectively. RESULTS: The 
      median age was 61 (40-81). Forty patients (80%) were diagnosed with non small 
      cell lung cancer (NSCLC), 10 patients (20%) were small cell carcinoma (SCC). 
      Twelve (24%) patients were smokers and 13 of 16 non-smokers had a history of 
      exposure to asbestos. The most common histologic subtype was adenocarcinoma (46%) 
      and this accounted for 71% in patients with exposure to asbestos. The most common 
      initial Eastern Cooperative Oncology Group (ECOG) performance score was 1 (24 
      patients, 48%) and initial stage was IV (25 patients, 50%) in the study group. 
      During the median 15 months (1-96 months) followup period: 1 year overall 
      survival (OS) was 68%, 2year overall survival was 36% and the median survival 
      time was 19 months. According to univariate analysis, poor ECOG performance 
      status, advanced stage, anemia and weight loss at time of diagnosis were negative 
      prognostic factors. However, adenocarcinoma sub-type was a positive prognostic 
      factor. CONCLUSIONS: In this study NSCLC sub-type, poor ECOG performance score, 
      advanced stage, anemia and weight loss were prognostic factors in Turkish women 
      with lung cancer.
FAU - Babacan, Nalan Akgul
AU  - Babacan NA
AD  - Departments of Medical Oncology, University of Cumhuriyet, SIVAS, Turkey E-mail : 
      nalanbabacan@gmail.com.
FAU - Yucel, Birsen
AU  - Yucel B
FAU - Kilickap, Saadettin
AU  - Kilickap S
FAU - Seker, Mehmet Metin
AU  - Seker MM
FAU - Kacan, Turgut
AU  - Kacan T
FAU - Olcas, Ilknur Koc
AU  - Olcas IK
FAU - Eren, Ayfer Ay
AU  - Eren AA
FAU - Odabas, Hatice
AU  - Odabas H
LA  - eng
PT  - Journal Article
PL  - Thailand
TA  - Asian Pac J Cancer Prev
JT  - Asian Pacific journal of cancer prevention : APJCP
JID - 101130625
RN  - 1332-21-4 (Asbestos)
SB  - IM
MH  - Adenocarcinoma/*pathology/secondary/therapy
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Asbestos/adverse effects
MH  - Carcinoma, Non-Small-Cell Lung/*pathology/secondary/therapy
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Lung Neoplasms/*pathology/therapy
MH  - Middle Aged
MH  - Prognosis
MH  - Proportional Hazards Models
MH  - Retrospective Studies
MH  - Small Cell Lung Carcinoma/*pathology/secondary/therapy
MH  - Smoking/adverse effects
MH  - Survival Rate
MH  - Turkey
EDAT- 2014/02/18 06:00
MHDA- 2014/11/13 06:00
CRDT- 2014/02/18 06:00
PHST- 2014/02/18 06:00 [entrez]
PHST- 2014/02/18 06:00 [pubmed]
PHST- 2014/11/13 06:00 [medline]
AID - 10.7314/apjcp.2014.15.1.151 [doi]
PST - ppublish
SO  - Asian Pac J Cancer Prev. 2014;15(1):151-4. doi: 10.7314/apjcp.2014.15.1.151.