PMID- 24532293
OWN - NLM
STAT- MEDLINE
DCOM- 20141014
LR  - 20150102
IS  - 1520-7560 (Electronic)
IS  - 1520-7552 (Linking)
VI  - 30 Suppl 1
DP  - 2014 Mar
TI  - Ma-Pi 2 macrobiotic diet and type 2 diabetes mellitus: pooled analysis of 
      short-term intervention studies.
PG  - 55-66
LID - 10.1002/dmrr.2519 [doi]
AB  - The macrobiotic, Ma-Pi 2 diet (12% protein, 18% fat and 70% carbohydrate), has 
      shown benefit in adults with type 2 diabetes mellitus (T2DM). This pooled 
      analysis aims to confirm results from four, 21-day intervention studies with the 
      Ma-Pi 2 diet, carried out in Cuba, China, Ghana and Italy. Baseline and end of 
      study biochemical, body composition and blood pressure data, were compared using 
      multivariate statistical methods and assessment of the Cohen effect size (d). 
      Results showed that all measured indicators demonstrated significant changes 
      (p < 0.001); most of them with a very high (d >/= 1.30), or high (d = 0.80-1.29) 
      effect size. The global effect size of the diet was Italy (1.96), China (1.79), 
      Cuba (1.38) and Ghana (0.98). The magnitude of the individual effect on each 
      variable by country, and the global effect by country, was independent of the 
      sample size (p > 0.05). Similarly, glycemia and glycemic profiles in all four 
      studies were independent of the sample size (p = 0.237). The Ma-Pi diet 2 
      significantly reduced glycemia, serum lipids, uremia and cardiovascular risk in 
      adults with T2DM. These results suggest that the Ma-Pi 2 diet could be a valid 
      alternative treatment for patients with T2DM and point to the need for further 
      clinical studies. Mechanisms related to its benefits as a functional diet are 
      discussed.
CI  - (c) 2013 The Authors. Diabetes/Metabolism Research and Reviews published by John 
      Wiley & Sons, Ltd.
FAU - Porrata-Maury, C
AU  - Porrata-Maury C
AD  - Finlay Institute, Havana, Cuba.
FAU - Hernandez-Triana, M
AU  - Hernandez-Triana M
FAU - Ruiz-Alvarez, V
AU  - Ruiz-Alvarez V
FAU - Diaz-Sanchez, M E
AU  - Diaz-Sanchez ME
FAU - Fallucca, F
AU  - Fallucca F
FAU - Bin, W
AU  - Bin W
FAU - Baba-Abubakari, B
AU  - Baba-Abubakari B
FAU - Pianesi, M
AU  - Pianesi M
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Diabetes Metab Res Rev
JT  - Diabetes/metabolism research and reviews
JID - 100883450
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Lipids)
SB  - IM
CIN - Diabetes Metab Res Rev. 2014 Nov;30(8):659-60. PMID: 25400068
MH  - Blood Glucose/metabolism
MH  - Cardiovascular Diseases/prevention & control
MH  - China
MH  - Cuba
MH  - Diabetes Mellitus, Type 2/*diet therapy
MH  - *Diet, Macrobiotic
MH  - Dietary Carbohydrates
MH  - Dietary Fats
MH  - Ghana
MH  - Humans
MH  - Italy
MH  - Lipids/blood
MH  - Risk Factors
OTO - NOTNLM
OT  - Ma-Pi 2 macrobiotic diet
OT  - adults
OT  - type 2 diabetes
OT  - vegetarian diets
OT  - whole-grain cereals
EDAT- 2014/02/18 06:00
MHDA- 2014/10/15 06:00
CRDT- 2014/02/18 06:00
PHST- 2013/10/23 00:00 [received]
PHST- 2013/12/19 00:00 [accepted]
PHST- 2014/02/18 06:00 [entrez]
PHST- 2014/02/18 06:00 [pubmed]
PHST- 2014/10/15 06:00 [medline]
AID - 10.1002/dmrr.2519 [doi]
PST - ppublish
SO  - Diabetes Metab Res Rev. 2014 Mar;30 Suppl 1:55-66. doi: 10.1002/dmrr.2519.