PMID- 24533465 OWN - NLM STAT- MEDLINE DCOM- 20140925 LR - 20211021 IS - 1471-2415 (Electronic) IS - 1471-2415 (Linking) VI - 14 DP - 2014 Feb 17 TI - Spectral-domain optical coherence tomography evaluation of postoperative cystoid macular oedema following phacoemulsification with intraoperative complication. PG - 16 LID - 10.1186/1471-2415-14-16 [doi] AB - BACKGROUND: To report the rate of cystoid macular oedema (CMO) as detected by spectral-domain optical coherence tomography (SD-OCT) after intraoperative complication during phacoemulsification. The secondary objectives include comparing mean macular thickness and best-corrected visual acuity (BCVA) between those who developed postoperative CMO against those who did not. METHODS: This is a prospective cohort study conducted in a tertiary hospital between July 2009 and June 2010. Serial SD-OCT and BCVA were performed at baseline, 1 week, 6 weeks and 16 weeks postoperatively. RESULTS: Single eyes from 47 subjects were analyzed; of these 16 (34%) eyes developed CMO. In the CMO group, mean macular thickness (+/-SD) increased sharply by 56 mum from 273 +/- 24 mum at baseline to 329 +/- 31 mum at 16 weeks; whereas in the non-CMO group, macular thickness showed a slight increase of 14 mum from 259 +/- 21 mum to 272 +/- 20 mum. In the CMO group, mean BCVA (in logarithm of minimum angle of resolution) improved modestly from 0.92 +/- 0.66 to 0.66 +/- 0.41 at week 16; while in the non-CMO group, mean BCVA improved markedly from 0.98 +/- 0.59 to 0.21 +/- 0.13. The two groups differed significantly in mean macular thickness (p < 0.001) and mean BCVA (p < 0.001) at 16 weeks. CONCLUSION: As detection rate of CMO is high, postoperative OCT monitoring for patients with intraoperative complications allows earlier diagnosis and treatment. FAU - Khaw, Keat Ween AU - Khaw KW AD - Department of Ophthalmology, University of Malaya Medical Centre, Lembah Pantai, Kuala Lumpur 59100, Malaysia. gideon_khaw@hotmail.com. FAU - Lam, Hee Hong AU - Lam HH FAU - Khang, Tsung Fei AU - Khang TF FAU - Wan Ab Kadir, Azida Juana AU - Wan Ab Kadir AJ FAU - Subrayan, Visvaraja AU - Subrayan V LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140217 PL - England TA - BMC Ophthalmol JT - BMC ophthalmology JID - 100967802 SB - IM MH - Aged MH - Aged, 80 and over MH - Case-Control Studies MH - Female MH - Humans MH - Intraoperative Complications/*diagnosis MH - Macular Edema/*diagnosis/physiopathology MH - Male MH - Middle Aged MH - Phacoemulsification/*adverse effects MH - Postoperative Period MH - Prospective Studies MH - Tomography, Optical Coherence/*methods MH - Visual Acuity PMC - PMC3932987 EDAT- 2014/02/19 06:00 MHDA- 2014/09/26 06:00 PMCR- 2014/02/17 CRDT- 2014/02/19 06:00 PHST- 2013/03/31 00:00 [received] PHST- 2014/02/12 00:00 [accepted] PHST- 2014/02/19 06:00 [entrez] PHST- 2014/02/19 06:00 [pubmed] PHST- 2014/09/26 06:00 [medline] PHST- 2014/02/17 00:00 [pmc-release] AID - 1471-2415-14-16 [pii] AID - 10.1186/1471-2415-14-16 [doi] PST - epublish SO - BMC Ophthalmol. 2014 Feb 17;14:16. doi: 10.1186/1471-2415-14-16.