PMID- 24547941 OWN - NLM STAT- MEDLINE DCOM- 20150601 LR - 20140807 IS - 1520-5215 (Electronic) IS - 1089-5639 (Linking) VI - 118 IP - 31 DP - 2014 Aug 7 TI - Potentiated electron transference in alpha-Ag2WO4 microcrystals with Ag nanofilaments as microbial agent. PG - 5769-78 LID - 10.1021/jp410564p [doi] AB - This study is a framework proposal for understanding the antimicrobacterial effect of both alpha-Ag2WO4 microcrystals (AWO) synthesized using a microwave hydrothermal (MH) method and alpha-Ag2WO4 microcrystals with Ag metallic nanofilaments (AWO:Ag) obtained by irradiation employing an electron beam to combat against planktonic cells of methicillin-resistant Staphylococcus aureus (MRSA). These samples were characterized by X-ray diffraction (XRD), FT-Raman spectroscopy, ultraviolet visible (UV-vis) measurements, field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), and high resolution transmission electron microscopy (HRTEM). The results reveal that both AWO and AWO:Ag solutions have bacteriostatic and bactericidal effects, but the irradiated sample is more efficient; i.e., a 4-fold of the MRSA planktonic cells as compared to the nonirradiated sample was observed. In addition, first principles calculations were performed to obtain structural and electronic properties of AWO and metallic Ag, which provides strong quantitative support for an antimicrobacterial mechanism based on the enhancement of electron transfer processes between alpha-Ag2WO4 and Ag nanoparticles. FAU - Longo, Valeria M AU - Longo VM AD - INCTMN-USP, Universidade de Sao Paulo, Instituto de Fisica de Sao Carlos , 13560-970 Sao Carlos, SP, Brazil. FAU - De Foggi, Camila C AU - De Foggi CC FAU - Ferrer, Mateus M AU - Ferrer MM FAU - Gouveia, Amanda F AU - Gouveia AF FAU - Andre, Rafaela S AU - Andre RS FAU - Avansi, Waldir AU - Avansi W FAU - Vergani, Carlos E AU - Vergani CE FAU - Machado, Ana L AU - Machado AL FAU - Andres, Juan AU - Andres J FAU - Cavalcante, Laecio S AU - Cavalcante LS FAU - Hernandes, Antonio C AU - Hernandes AC FAU - Longo, Elson AU - Longo E LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140305 PL - United States TA - J Phys Chem A JT - The journal of physical chemistry. A JID - 9890903 RN - 0 (Anti-Bacterial Agents) RN - 0 (Silver Compounds) SB - IM MH - Anti-Bacterial Agents/*chemistry MH - Computer Simulation MH - Electrons MH - Metal Nanoparticles/*chemistry MH - Methicillin-Resistant Staphylococcus aureus/drug effects/radiation effects MH - Microbial Sensitivity Tests MH - Microscopy, Electron, Scanning MH - Microscopy, Electron, Transmission MH - Models, Chemical MH - Silver Compounds/*chemistry MH - Spectrum Analysis, Raman MH - X-Ray Diffraction EDAT- 2014/02/20 06:00 MHDA- 2015/06/02 06:00 CRDT- 2014/02/20 06:00 PHST- 2014/02/20 06:00 [entrez] PHST- 2014/02/20 06:00 [pubmed] PHST- 2015/06/02 06:00 [medline] AID - 10.1021/jp410564p [doi] PST - ppublish SO - J Phys Chem A. 2014 Aug 7;118(31):5769-78. doi: 10.1021/jp410564p. Epub 2014 Mar 5.