PMID- 24552415 OWN - NLM STAT- MEDLINE DCOM- 20140609 LR - 20151119 IS - 1529-8019 (Electronic) IS - 1396-0296 (Linking) VI - 26 IP - 6 DP - 2013 Nov-Dec TI - Periungual and subungual pyogenic granuloma following anti-TNF-alpha therapy: is it the first case? PG - 493-5 LID - 10.1111/dth.12022 [doi] AB - Tumor necrosis factor-alpha (TNF-alpha) antagonists have advanced treatment of psoriasis and other chronic inflammatory diseases but are not free of adverse effects. Pyogenic granuloma is yet described in literature as a dermatological side effect of multiple drugs such as retinoids, antiretroviral, and antineoplastic drugs but, to the best of our knowledge, it has never been reported among the adverse skin reactions following anti-TNF-alpha therapy. We report on a 20-year-old Caucasian man with psoriatic arthritis who developed multiple eruptive periungual and subungual pyogenic granulomas following treatment with TNF-alpha antagonist etanercept. CI - (c) 2013 Wiley Periodicals, Inc. FAU - Patruno, Cataldo AU - Patruno C AD - Department of Dermatology, University of Naples Federico II, Naples, Italy. FAU - Balato, Nicola AU - Balato N FAU - Cirillo, Teresa AU - Cirillo T FAU - Napolitano, Maddalena AU - Napolitano M FAU - Ayala, Fabio AU - Ayala F LA - eng PT - Case Reports PT - Journal Article DEP - 20130401 PL - United States TA - Dermatol Ther JT - Dermatologic therapy JID - 9700070 RN - 0 (Antirheumatic Agents) RN - 0 (Immunoglobulin G) RN - 0 (Receptors, Tumor Necrosis Factor) RN - 0 (Tumor Necrosis Factor-alpha) RN - OP401G7OJC (Etanercept) SB - IM MH - Adult MH - Antirheumatic Agents/administration & dosage/*adverse effects MH - Arthritis, Psoriatic/*drug therapy MH - Etanercept MH - Granuloma, Pyogenic/*chemically induced/diagnosis MH - Humans MH - Immunoglobulin G/administration & dosage/*adverse effects MH - Injections, Subcutaneous MH - Male MH - Nail Diseases/*chemically induced/diagnosis MH - Psoriasis/*drug therapy MH - Receptors, Tumor Necrosis Factor/administration & dosage MH - Tumor Necrosis Factor-alpha/*antagonists & inhibitors MH - Young Adult OTO - NOTNLM OT - etanercept OT - psoriasis OT - pyogenic granuloma EDAT- 2014/02/21 06:00 MHDA- 2014/06/10 06:00 CRDT- 2014/02/21 06:00 PHST- 2014/02/21 06:00 [entrez] PHST- 2014/02/21 06:00 [pubmed] PHST- 2014/06/10 06:00 [medline] AID - 10.1111/dth.12022 [doi] PST - ppublish SO - Dermatol Ther. 2013 Nov-Dec;26(6):493-5. doi: 10.1111/dth.12022. Epub 2013 Apr 1.