PMID- 24560943
OWN - NLM
STAT- MEDLINE
DCOM- 20150126
LR  - 20140318
IS  - 1773-0597 (Electronic)
IS  - 0181-5512 (Linking)
VI  - 37
IP  - 3
DP  - 2014 Mar
TI  - [Choroidal thickness assessment with SD-OCT in high myopia with dome-shaped 
      macula].
PG  - 237-41
LID - S0181-5512(14)00024-2 [pii]
LID - 10.1016/j.jfo.2013.10.002 [doi]
AB  - PURPOSE: To measure macular choroidal thickness (CT) using spectral-domain 
      optical coherence tomography (SD-OCT) in highly myopic eyes with dome-shaped 
      macula (DSM), and to investigate whether the choroid is thicker in these eyes 
      compared to highly myopic eyes without MB. PATIENTS AND METHODS: A 
      cross-sectional study of 200 eyes was performed between January 2010 and June 
      2012. Twenty-four highly myopic eyes (12%) had a dome-shaped macula. All patients 
      underwent a complete ophthalmological examination, SD-OCT (TOPCON 2000), and 
      B-scan ultrasonography. OCT scans were analyzed in 7 sections, and subfoveal CT 
      was measured manually between the Bruch's membrane and the internal aspect of the 
      sclera. The 20 eyes with isolated dome-shaped macular were paired by age and 
      axial length (AL) with 20 eyes without macular involvement. RESULTS: In the 
      subgroup with isolated MB, the mean subfoveal CT was 101.86 mum (+/- 21.35 mum). A 
      statistically significant negative correlation was found between CT and AL 
      (r=-0.623, P=0.0001). The regression equation demonstrated a decrease of 8.3 mum 
      per mm of AL. In the subgroup without MB, matched with the subgroup with MB by 
      age (P=0.591), and AL (P=0.815), the mean subfoveal CT was 89.54 mum (+/- 20.12 mum). 
      The comparison between the two subgroups found a statistically significant 
      difference in subfoveal CT (P<10-4). CONCLUSIONS: In our study, choroidal 
      thickness is increased in highly myopic eyes with dome-shaped macula compared to 
      highly myopic eyes without dome-shaped macula. These findings suggest that 
      abnormalities of the choroid may play a role in the pathogenesis of dome-shaped 
      macula.
CI  - Copyright (c) 2014 Elsevier Masson SAS. All rights reserved.
FAU - Chebil, A
AU  - Chebil A
AD  - Service d'ophtalmologie B, institut Hedi-Rais d'ophtalmologie de Tunis, boulevard 
      9-avril, 1006 Tunis, Tunisie. Electronic address: chebilahmed@yahoo.fr.
FAU - Ben Achour, B
AU  - Ben Achour B
AD  - Service d'ophtalmologie B, institut Hedi-Rais d'ophtalmologie de Tunis, boulevard 
      9-avril, 1006 Tunis, Tunisie.
FAU - Chaker, N
AU  - Chaker N
AD  - Service d'ophtalmologie B, institut Hedi-Rais d'ophtalmologie de Tunis, boulevard 
      9-avril, 1006 Tunis, Tunisie.
FAU - Jedidi, L
AU  - Jedidi L
AD  - Service d'ophtalmologie B, institut Hedi-Rais d'ophtalmologie de Tunis, boulevard 
      9-avril, 1006 Tunis, Tunisie.
FAU - Mghaieth, F
AU  - Mghaieth F
AD  - Service d'ophtalmologie B, institut Hedi-Rais d'ophtalmologie de Tunis, boulevard 
      9-avril, 1006 Tunis, Tunisie.
FAU - El Matri, L
AU  - El Matri L
AD  - Service d'ophtalmologie B, institut Hedi-Rais d'ophtalmologie de Tunis, boulevard 
      9-avril, 1006 Tunis, Tunisie.
LA  - fre
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
TT  - Epaisseur choroidienne foveolaire au SD-OCT dans la myopie forte avec macula 
      bombee.
DEP - 20140220
PL  - France
TA  - J Fr Ophtalmol
JT  - Journal francais d'ophtalmologie
JID - 7804128
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Child
MH  - Choroid/*pathology
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Macula Lutea
MH  - Male
MH  - Middle Aged
MH  - Myopia/complications/pathology
MH  - Retinal Diseases/complications/pathology
MH  - Retrospective Studies
MH  - *Tomography, Optical Coherence/methods
MH  - Young Adult
OTO - NOTNLM
OT  - Choroid
OT  - Choroide
OT  - Dome-shaped macula
OT  - High myopia
OT  - Macula bombee
OT  - Myopie forte
OT  - SD-OCT
EDAT- 2014/02/25 06:00
MHDA- 2015/01/27 06:00
CRDT- 2014/02/25 06:00
PHST- 2013/09/07 00:00 [received]
PHST- 2013/10/24 00:00 [accepted]
PHST- 2014/02/25 06:00 [entrez]
PHST- 2014/02/25 06:00 [pubmed]
PHST- 2015/01/27 06:00 [medline]
AID - S0181-5512(14)00024-2 [pii]
AID - 10.1016/j.jfo.2013.10.002 [doi]
PST - ppublish
SO  - J Fr Ophtalmol. 2014 Mar;37(3):237-41. doi: 10.1016/j.jfo.2013.10.002. Epub 2014 
      Feb 20.