PMID- 24562052
OWN - NLM
STAT- MEDLINE
DCOM- 20141201
LR  - 20140407
IS  - 1872-7077 (Electronic)
IS  - 1382-6689 (Linking)
VI  - 37
IP  - 2
DP  - 2014 Mar
TI  - Molecular cloning and expression of the gene for G protein alpha subunit induced 
      by bisphenol A in marine polychaete Perinereis aibuhitensis.
PG  - 521-8
LID - S1382-6689(14)00007-6 [pii]
LID - 10.1016/j.etap.2014.01.006 [doi]
AB  - A G protein alpha subunit gene named Pa Galpha was isolated from the marine 
      polychaete Perinereis aibuhitensis. The full-length cDNA of Pa Galpha was 1832 bp and 
      contained a 205 bp 5' untranslated region (5'UTR), a 565 bp 3' UTR and a 1062 bp 
      open reading frame encoding 353 amino acid residues. The deduced protein sequence 
      of Pa Galpha showed 73% homology with the Galpha protein of Dipolydora quadrilobata. 
      Tissue-specific expression induced by exposure to bisphenol A (BPA) in P. 
      aibuhitensis was detected by real-time PCR, which showed BPA induced expression 
      of the Pa Galpha gene, and the level of transcription was related positively to the 
      concentration of BPA and the length of exposure time. With increasing 
      concentration of BPA and length of exposure time, the level of mRNA transcription 
      was raised gradually, but the level of increasing expression of Pa Galpha mRNA 
      induced by exposure to BPA varied significantly among different tissues.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Zhao, Huan
AU  - Zhao H
AD  - Key Laboratory of Marine Bio-resources Restoration and Habitat Reparation in 
      Liaoning province, Dalian Ocean University, Dalian, 116023, China.
FAU - Zhou, Yibing
AU  - Zhou Y
AD  - Key Laboratory of Marine Bio-resources Restoration and Habitat Reparation in 
      Liaoning province, Dalian Ocean University, Dalian, 116023, China. Electronic 
      address: ybzhou2011@hotmail.com.
FAU - Li, Ying
AU  - Li Y
AD  - Key Laboratory of Marine Bio-resources Restoration and Habitat Reparation in 
      Liaoning province, Dalian Ocean University, Dalian, 116023, China.
FAU - Li, Shaojuan
AU  - Li S
AD  - Key Laboratory of Marine Bio-resources Restoration and Habitat Reparation in 
      Liaoning province, Dalian Ocean University, Dalian, 116023, China.
FAU - Yang, Dazuo
AU  - Yang D
AD  - Key Laboratory of Marine Bio-resources Restoration and Habitat Reparation in 
      Liaoning province, Dalian Ocean University, Dalian, 116023, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140129
PL  - Netherlands
TA  - Environ Toxicol Pharmacol
JT  - Environmental toxicology and pharmacology
JID - 9612020
RN  - 0 (Benzhydryl Compounds)
RN  - 0 (DNA, Complementary)
RN  - 0 (GTP-Binding Protein alpha Subunits)
RN  - 0 (Phenols)
RN  - 0 (RNA, Messenger)
RN  - 0 (Water Pollutants, Chemical)
RN  - MLT3645I99 (bisphenol A)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Benzhydryl Compounds/*toxicity
MH  - Cloning, Molecular
MH  - DNA, Complementary/genetics
MH  - GTP-Binding Protein alpha Subunits/*genetics
MH  - Gene Expression
MH  - Molecular Sequence Data
MH  - Phenols/*toxicity
MH  - Polychaeta/*genetics
MH  - RNA, Messenger/metabolism
MH  - Water Pollutants, Chemical/*toxicity
OTO - NOTNLM
OT  - Bisphenol A
OT  - G protein alpha subunit
OT  - Gene expression
OT  - Perinereis aibuhitensis
EDAT- 2014/02/25 06:00
MHDA- 2014/12/15 06:00
CRDT- 2014/02/25 06:00
PHST- 2013/10/08 00:00 [received]
PHST- 2013/12/30 00:00 [revised]
PHST- 2014/01/13 00:00 [accepted]
PHST- 2014/02/25 06:00 [entrez]
PHST- 2014/02/25 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
AID - S1382-6689(14)00007-6 [pii]
AID - 10.1016/j.etap.2014.01.006 [doi]
PST - ppublish
SO  - Environ Toxicol Pharmacol. 2014 Mar;37(2):521-8. doi: 10.1016/j.etap.2014.01.006. 
      Epub 2014 Jan 29.