PMID- 24574991
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140227
LR  - 20211021
IS  - 1662-5161 (Print)
IS  - 1662-5161 (Electronic)
IS  - 1662-5161 (Linking)
VI  - 8
DP  - 2014
TI  - Negative emotion modulates prefrontal cortex activity during a working memory 
      task: a NIRS study.
PG  - 46
LID - 10.3389/fnhum.2014.00046 [doi]
LID - 46
AB  - This study investigated the neural processing underlying the cognitive control of 
      emotions induced by the presentation of task-irrelevant emotional pictures before 
      a working memory task. Previous studies have suggested that the cognitive control 
      of emotion involves the prefrontal regions. Therefore, we measured the 
      hemodynamic responses that occurred in the prefrontal region with a 16-channel 
      near-infrared spectroscopy (NIRS) system. In our experiment, participants 
      observed two negative or two neutral pictures in succession immediately before a 
      1-back or 3-back task. Pictures were selected from the International Affective 
      Picture System (IAPS). We measured the changes in the concentration of oxygenated 
      hemoglobin (oxyHb) during picture presentation and during the n-back task. The 
      emotional valence of the picture affected the oxyHb changes in anterior parts of 
      the medial prefrontal cortex (MPFC) (located in the left and right superior 
      frontal gyrus) and left inferior frontal gyrus during the n-back task; the oxyHb 
      changes during the task were significantly greater following negative rather than 
      neutral stimulation. As indicated in a number of previous studies, and the time 
      courses of the oxyHb changes in our study, activation in these locations is 
      possibly led by cognitive control of emotion, though we cannot deny it may simply 
      be emotional responses. There were no effects of emotion on oxyHb changes during 
      picture presentation or on n-back task performance. Although further studies are 
      necessary to confirm this interpretation, our findings suggest that NIRS can be 
      used to investigate neural processing during emotional control.
FAU - Ozawa, Sachiyo
AU  - Ozawa S
AD  - Graduate School of Arts and Science, The University of Tokyo, JST, CREST Tokyo, 
      Japan.
FAU - Matsuda, Goh
AU  - Matsuda G
AD  - Graduate School of Arts and Science, The University of Tokyo, JST, CREST Tokyo, 
      Japan.
FAU - Hiraki, Kazuo
AU  - Hiraki K
AD  - Graduate School of Arts and Science, The University of Tokyo, JST, CREST Tokyo, 
      Japan.
LA  - eng
PT  - Journal Article
DEP - 20140210
PL  - Switzerland
TA  - Front Hum Neurosci
JT  - Frontiers in human neuroscience
JID - 101477954
PMC - PMC3918646
OTO - NOTNLM
OT  - DLPFC
OT  - IAPS
OT  - NIRS
OT  - cognitive control
OT  - emotion regulation
OT  - n-back task
OT  - prefrontal activity
OT  - working memory
EDAT- 2014/02/28 06:00
MHDA- 2014/02/28 06:01
PMCR- 2014/01/01
CRDT- 2014/02/28 06:00
PHST- 2013/09/30 00:00 [received]
PHST- 2014/01/21 00:00 [accepted]
PHST- 2014/02/28 06:00 [entrez]
PHST- 2014/02/28 06:00 [pubmed]
PHST- 2014/02/28 06:01 [medline]
PHST- 2014/01/01 00:00 [pmc-release]
AID - 10.3389/fnhum.2014.00046 [doi]
PST - epublish
SO  - Front Hum Neurosci. 2014 Feb 10;8:46. doi: 10.3389/fnhum.2014.00046. eCollection 
      2014.