PMID- 24579965
OWN - NLM
STAT- MEDLINE
DCOM- 20141027
LR  - 20221207
IS  - 1840-4812 (Electronic)
IS  - 1512-8601 (Print)
IS  - 1512-8601 (Linking)
VI  - 14
IP  - 1
DP  - 2014 Feb
TI  - Increased coronary intervention rate among diabetic patients with poor glycaemic 
      control: a cross-sectional study.
PG  - 16-20
AB  - The relationship between glycaemic control and coronary artery disease (CAD) in 
      type 2 diabetes mellitus (T2DM) is controversial. In the current cross-sectional 
      study, we addressed the relationship between Hemoglobin A1c (HbA1c) values and 
      the need for revascularization among diabetic patients undergoing coronary 
      angiography. A total of 301 consecutive patients with known T2DM (age 61.8+/-10.1 
      years, 46.2 % women) requiring coronary angiography due to CAD symptoms were 
      included. T2DM patients were categorized into two groups based on their HbA1c 
      values: 93 (30.9%) diabetics with good glycaemic control (HbA1c</=7 %), and 208 
      (69.1%) diabetics with poor glycaemic control (HbA1c>7 %). A total of 123 
      patients (40.9%) required revascularization. The revascularization rate was 28.0% 
      among T2DM patients with good glycaemic control and 46.6% among T2DM patients 
      with poor glycaemic control, respectively (p=0.002). In a logistic regression 
      analysis, the need for revascularization was predicted by poor glycaemic control 
      (Odds Ratio [OR] 2.26, 95% Confidence Interval [CI] 1.32-3.82; p=0.003) adjusted 
      for age, gender, Body-Mass-Index and diabetes duration. Moreover, there was a 
      linear relationship between HbA1c values and number of affected coronary arteries 
      (r= 0.169; p=0.003). Our data suggest that there is a close association between 
      poor glycaemic control and increased revascularization rate in T2DM, which should 
      be considered in primary and secondary prevention models.
FAU - Cetin, Suha
AU  - Cetin S
AD  - Department of Cardiology, 29 Mayis Hospital, Dikmen Caddesi, No:312, 06460 
      Ankara, Turkey.
FAU - Ozturk, Mehmet Akif
AU  - Ozturk MA
AD  - Department of Internal Medicine, School of Medicine, Gazi University, Emniyet 
      Mahallesi, 06560 Ankara, Turkey.
FAU - Barindik, Nadir
AU  - Barindik N
AD  - Department of Cardiology, 29 Mayis Hospital, Dikmen Caddesi, No:312, 06460 
      Ankara, Turkey.
FAU - Imren, Ersin
AU  - Imren E
AD  - Department of Cardiology, 29 Mayis Hospital, Dikmen Caddesi, No:312, 06460 
      Ankara, Turkey.
FAU - Peker, Yuksel
AU  - Peker Y
AD  - Department of Molecular and Clinical Medicine/Cardiology, Sahlgrenska Academy, 
      University of Gothenborg, Medicinaregaten 3, 40530 Gothenborg, Sweden.
LA  - eng
PT  - Journal Article
PL  - Bosnia and Herzegovina
TA  - Bosn J Basic Med Sci
JT  - Bosnian journal of basic medical sciences
JID - 101200947
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Hypoglycemic Agents)
SB  - IM
MH  - Aged
MH  - Blood Glucose/analysis
MH  - Body Mass Index
MH  - *Coronary Angiography
MH  - Coronary Artery Disease/complications/*diagnostic imaging
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/complications/*diagnostic imaging/*drug therapy
MH  - Female
MH  - Glycated Hemoglobin/*analysis
MH  - Humans
MH  - Hypoglycemic Agents/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Odds Ratio
MH  - Regression Analysis
MH  - Retrospective Studies
PMC - PMC4333943
EDAT- 2014/03/04 06:00
MHDA- 2014/10/28 06:00
PMCR- 2014/02/01
CRDT- 2014/03/04 06:00
PHST- 2014/03/04 06:00 [entrez]
PHST- 2014/03/04 06:00 [pubmed]
PHST- 2014/10/28 06:00 [medline]
PHST- 2014/02/01 00:00 [pmc-release]
AID - BJBMS-14-16 [pii]
AID - 10.17305/bjbms.2014.2286 [doi]
PST - ppublish
SO  - Bosn J Basic Med Sci. 2014 Feb;14(1):16-20. doi: 10.17305/bjbms.2014.2286.