PMID- 24583587
OWN - NLM
STAT- MEDLINE
DCOM- 20140912
LR  - 20190918
IS  - 1882-0654 (Electronic)
IS  - 0009-918X (Linking)
VI  - 54
IP  - 2
DP  - 2014
TI  - [A case of possible neuro-Sweet disease with prolonged disturbance of 
      consciousness and no dermal lesion during the course of dementia].
PG  - 130-4
AB  - The patient was a 58-year-old man with 1-year history of cognitive decline, which 
      was diagnosed as Alzheimer's disease in another hospital. He was admitted to our 
      hospital for extreme fatigue, weight loss, and dysphagia, subsequent to the left 
      peripheral facial paresis. Brain magnetic resonance (MR) imaging showed bilateral 
      diffuse white matter lesions and hippocampal atrophy. After admission, he 
      presented with sudden high fever, recurrent exacerbations of consciousness, and 
      increased C-reactive protein level with marked neutrophilia, with the result that 
      he underwent mechanical ventilation. Routine cerebrospinal fluid findings at the 
      exacerbation were normal i.e. 4.7 cells/mm(3), 40 mg/dl of protein, but IL-6 
      concentration was mildly elevated to 22.2 pg/ml. After confirming the positivity 
      of HLA (human leukocyte antigen) B54 and Cw1, we administered steroid to him and 
      his physical activity and state of consciousness significantly improved. During 
      the course of treatment, dermal lesion characterisitic of Sweet disease was 
      absent. We diagnosed this case was possible neuroSweet disease proposed by 
      Hisanaga in 2005.
FAU - Nakatani, Rie
AU  - Nakatani R
AD  - Department of Neurology, Toyonaka Municipal Hospital.
FAU - Naba, Ichiro
AU  - Naba I
FAU - Kawasaki, Yuko
AU  - Kawasaki Y
FAU - Moriya, Masayuki
AU  - Moriya M
FAU - Nakano, Misa
AU  - Nakano M
FAU - Tatsumi, Chikao
AU  - Tatsumi C
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Rinsho Shinkeigaku
JT  - Rinsho shinkeigaku = Clinical neurology
JID - 0417466
RN  - 0 (HLA Antigens)
RN  - 0 (Interleukin-6)
SB  - IM
MH  - Central Nervous System Diseases/*diagnosis
MH  - Consciousness Disorders/*complications
MH  - HLA Antigens/analysis
MH  - Humans
MH  - Interleukin-6/cerebrospinal fluid
MH  - Male
MH  - Middle Aged
MH  - Sweet Syndrome/*diagnosis
EDAT- 2014/03/04 06:00
MHDA- 2014/09/13 06:00
CRDT- 2014/03/04 06:00
PHST- 2014/03/04 06:00 [entrez]
PHST- 2014/03/04 06:00 [pubmed]
PHST- 2014/09/13 06:00 [medline]
AID - DN/JST.JSTAGE/clinicalneurol/54.130 [pii]
AID - 10.5692/clinicalneurol.54.130 [doi]
PST - ppublish
SO  - Rinsho Shinkeigaku. 2014;54(2):130-4. doi: 10.5692/clinicalneurol.54.130.