PMID- 24586746
OWN - NLM
STAT- MEDLINE
DCOM- 20141014
LR  - 20221207
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 9
IP  - 2
DP  - 2014
TI  - Comparative study of sex differences in distal femur morphology in osteoarthritic 
      knees in a Chinese population.
PG  - e89394
LID - 10.1371/journal.pone.0089394 [doi]
LID - e89394
AB  - OBJECTIVES: The purpose of this study was to investigate sex differences in 
      resected distal femoral morphology in Chinese osteoarthritic knees. METHODS: The 
      study included 130 osteoarthritic knees in 65 men and 65 women in China. None had 
      anterior femoral osteophyte or serious patellar femoral joint degeneration. The 
      following were measured using computed tomography and analyzed to identify 
      morphological differences according to sex in the resected distal femurs: 
      anterior lateral condylar height (ALCH), anterior medial condylar height (AMCH), 
      and mediolateral (ML) and anteroposterior (AP) dimensions. The ML/AP aspect ratio 
      was calculated. RESULTS: The average ALCH and AMCH were 8.2+/-1.8 mm, 3.1+/-1.5 mm 
      for men and 7.4+/-1.7 mm, 3.6+/-1.5 mm for women. There were significant differences 
      between men and women in ALCH values (P = 0.014) but not in AMCH values 
      (P = 0.09). Women had smaller ML/AP aspect ratios than men for a given AP 
      dimension. This indicated that the femoral ML dimension of a prosthesis with a 
      given AP dimension may have overhang in women. CONCLUSIONS: This study suggested 
      that sex differences should be taken into account in the design of femoral 
      prosthesis for Chinese men and women.
FAU - Yang, Bo
AU  - Yang B
AD  - Institute of Sports Medicine, Peking University Third Hospital, Haidian District, 
      Beijing, China.
FAU - Yu, Jia-Kuo
AU  - Yu JK
AD  - Institute of Sports Medicine, Peking University Third Hospital, Haidian District, 
      Beijing, China.
FAU - Zheng, Zhuo-Zhao
AU  - Zheng ZZ
AD  - Department of Radiology, Peking University Third Hospital, Haidian District, 
      Beijing, China.
FAU - Lu, Zhi-Hua
AU  - Lu ZH
AD  - Institute of Sports Medicine, Peking University Third Hospital, Haidian District, 
      Beijing, China.
FAU - Zhang, Ji-Ying
AU  - Zhang JY
AD  - Institute of Sports Medicine, Peking University Third Hospital, Haidian District, 
      Beijing, China.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140219
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Aged
MH  - *Asian People
MH  - Female
MH  - Femur/*pathology
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Osteoarthritis, Knee/*pathology
MH  - *Sex Characteristics
MH  - Tomography, X-Ray Computed
PMC - PMC3929686
COIS- Competing Interests: The authors have declared that no competing interests exist.
EDAT- 2014/03/04 06:00
MHDA- 2014/10/15 06:00
PMCR- 2014/02/19
CRDT- 2014/03/04 06:00
PHST- 2013/09/11 00:00 [received]
PHST- 2014/01/20 00:00 [accepted]
PHST- 2014/03/04 06:00 [entrez]
PHST- 2014/03/04 06:00 [pubmed]
PHST- 2014/10/15 06:00 [medline]
PHST- 2014/02/19 00:00 [pmc-release]
AID - PONE-D-13-37889 [pii]
AID - 10.1371/journal.pone.0089394 [doi]
PST - epublish
SO  - PLoS One. 2014 Feb 19;9(2):e89394. doi: 10.1371/journal.pone.0089394. eCollection 
      2014.