PMID- 24589062
OWN - NLM
STAT- MEDLINE
DCOM- 20141201
LR  - 20140416
IS  - 1600-0897 (Electronic)
IS  - 1046-7408 (Linking)
VI  - 71
IP  - 5
DP  - 2014 May
TI  - Genetic considerations in human sex-mate selection: partners share human 
      leukocyte antigen but not short-tandem-repeat identity markers.
PG  - 467-71
LID - 10.1111/aji.12213 [doi]
AB  - PROBLEM: Previous studies support a role for MHC on mating preference, yet it 
      remains unsettled as to whether mating occurs preferentially between individuals 
      sharing human leukocyte antigen (HLA) determinants or not. Investigating sex-mate 
      preferences in the contemporary Israeli population is of further curiosity being 
      a population with distinct genetic characteristics, where multifaceted cultural 
      considerations influence mate selection. METHOD OF STUDY: Pairs of male-female 
      sex partners were evaluated in three groups. Two groups represented unmarried 
      (n = 1002) or married (n = 308) couples and a control group of fictitious 
      male-female couples. HLA and short-tandem-repeat (STR) genetic identification 
      markers were assessed for the frequency of shared antigens and alleles. RESULTS: 
      Human leukocyte antigen results showed that Class I and/ or Class II single 
      antigen as well as double antigen sharing was more common in sex partners than in 
      control group couples (P < 0.001). Married versus unmarried pairs were not 
      distinguishable. In contrast, STR-DNA markers failed to differentiate between 
      sex-mates and controls (P = 0.78). CONCLUSION: Sex partnerships shared HLA 
      determinants more frequently than randomly constituted male-female pairs. The 
      observed phenomenon does not reflect a syngenetic background between sex-mates as 
      STR markers were not selectively shared. Thus, sex-mate selection in man may 
      contravene the evolutionary pressure for genetic diversity in regard to HLA.
CI  - (c) 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Israeli, Moshe
AU  - Israeli M
AD  - Tissue Typing Laboratory, Rabin Medical Center, Petach-Tikva, Israel.
FAU - Kristt, Don
AU  - Kristt D
FAU - Nardi, Yuval
AU  - Nardi Y
FAU - Klein, Tirza
AU  - Klein T
LA  - eng
PT  - Journal Article
DEP - 20140303
PL  - Denmark
TA  - Am J Reprod Immunol
JT  - American journal of reproductive immunology (New York, N.Y. : 1989)
JID - 8912860
RN  - 0 (Genetic Markers)
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Alleles
MH  - Female
MH  - Gene Frequency
MH  - Genetic Markers
MH  - Genetic Variation
MH  - HLA Antigens/*genetics/immunology
MH  - Haplotypes
MH  - Humans
MH  - Israel/ethnology
MH  - Male
MH  - Marriage/ethnology/*psychology
MH  - Microsatellite Repeats/*immunology
MH  - Middle Aged
MH  - Selection, Genetic
MH  - Sexual Behavior/ethnology/*psychology
MH  - Sexual Partners/psychology
OTO - NOTNLM
OT  - Genetics
OT  - human leukocyte antigen
OT  - mating
OT  - selection
OT  - short tandem repeats
EDAT- 2014/03/05 06:00
MHDA- 2014/12/15 06:00
CRDT- 2014/03/05 06:00
PHST- 2013/11/13 00:00 [received]
PHST- 2014/01/13 00:00 [accepted]
PHST- 2014/03/05 06:00 [entrez]
PHST- 2014/03/05 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
AID - 10.1111/aji.12213 [doi]
PST - ppublish
SO  - Am J Reprod Immunol. 2014 May;71(5):467-71. doi: 10.1111/aji.12213. Epub 2014 Mar 
      3.