PMID- 24589612 OWN - NLM STAT- MEDLINE DCOM- 20141222 LR - 20171116 IS - 1673-4254 (Print) IS - 1673-4254 (Linking) VI - 34 IP - 2 DP - 2014 Feb TI - [Correlation between adipocytokines levels and metabolic syndrome in type 2 diabetes mellitus]. PG - 275-8 AB - OBJECTIVE: To study the correlation between adipocytokines levels and metabolic syndrome (MS) in patients with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS: Sixty-eight patients with newly diagnosed T2DM, including 51 cases with MS and 17 without MS, were examined for blood pressure (BP), fasting blood glucose (FBG), fasting insulin (FINS), insulin resistance index (IRI), waist to hip ratio (W/H), body mass index (BMI), and serum adipocytokine levels (IL-6, vaspin, and adiponectin). RESULTS: The diabetic patients with MS had higher BMI, HbA1c, FBG, FINS, IRI, TG, TC, and SBP than those without MS. Serum IL-6 level was higher but adiponectin level was lower in patients with MS than in those without MS. There was no significant difference in vaspin level between the two groups. Adiponectin level was positively correlated with TG (r=-0.30, P=0.02) and inversely with BMI (r=-0.47, P=0.39) and HOMA-IR (r=-0.30, P=0.03); vaspin level was positively correlated with HOMA-IR (r=0.347, P=0.02) and inversely with HDL-L (r=-0.45, P=0.01); IL-6 level was positively correlated with LDL-L (r=0.18, P=0.25) and inversely with HDL-L (r=-0.45, P=0.01). CONCLUSION: Adiponectin and IL-6 levels are closely related to MS, but the relationship between vaspin and MS needs further investigation. FAU - Yan, Ting AU - Yan T AD - Department of Endocrinology, Zhujiang Hosipital, Southern Medical University, Guangzhou 510282, China.E-mail: yixueyingyang@126.com. FAU - Li, Lingling AU - Li L FAU - Wang, Huaiming AU - Wang H FAU - Wang, Jiao AU - Wang J FAU - Cai, Dehong AU - Cai D LA - chi PT - Comparative Study PT - Journal Article PL - China TA - Nan Fang Yi Ke Da Xue Xue Bao JT - Nan fang yi ke da xue xue bao = Journal of Southern Medical University JID - 101266132 RN - 0 (Adipokines) RN - 0 (Adiponectin) RN - 0 (IL6 protein, human) RN - 0 (Interleukin-6) RN - 0 (SERPINA12 protein, human) RN - 0 (Serpins) SB - IM MH - Adipokines/*blood MH - Adiponectin/blood MH - Adipose Tissue/metabolism MH - Adult MH - Diabetes Mellitus, Type 2/*blood/*complications MH - Female MH - Humans MH - Interleukin-6/blood MH - Male MH - Metabolic Syndrome/*complications MH - Middle Aged MH - Serpins/blood EDAT- 2014/03/05 06:00 MHDA- 2014/12/23 06:00 CRDT- 2014/03/05 06:00 PHST- 2014/03/05 06:00 [entrez] PHST- 2014/03/05 06:00 [pubmed] PHST- 2014/12/23 06:00 [medline] PST - ppublish SO - Nan Fang Yi Ke Da Xue Xue Bao. 2014 Feb;34(2):275-8.