PMID- 24595575
OWN - NLM
STAT- MEDLINE
DCOM- 20141124
LR  - 20191210
IS  - 1545-9616 (Print)
IS  - 1545-9616 (Linking)
VI  - 13
IP  - 3
DP  - 2014 Mar
TI  - A preliminary study on the safety and efficacy of a novel fractional CO(2) laser 
      with synchronous radiofrequency delivery.
PG  - 299-304
AB  - Building upon the fractional CO(2) technology incorporated into the first 
      generation SmartXide DOT (DEKA / ElEn, SpA, Calenzano, Italy) introduced in the 
      U.S. in 2008, a second generation SmartXide Quadro has recently been introduced. 
      This is a versatile device that has the ability to combine fractional CO(2) laser 
      output for skin resurfacing with the synchronous delivery of bipolar 
      radiofrequency (RF) energy for deeper, more diffuse heating. A pilot study was 
      undertaken to demonstrate the safety and efficacy of the SmartXide Quadro, 
      employing both fractional CO(2) laser output combined with the synchronous delivery 
      of radiofrequency energy for the treatment of facial rhytides and acne scars. Ten 
      patients, all women, six with facial rhytides and four with acne scarring, were 
      treated with the SmartXide Quadro, a variably pulsed CO(2) laser with Pulse Shape 
      Design(R) technology, a microablative DOT scanner and synchronized bipolar RF 
      emission. Each patient was treated with a single fractional CO(2) laser-RF 
      treatment; laser and RF parameters varied according to the severity of the 
      rhytides or acne scars and were based upon both manufacturer-recommended settings 
      and surgeon experience. Follow-up was at three days, one week, 2 weeks, and one 
      month, three months, and six months after treatment. Results were judged by 
      comparison of preoperative and post-operative photos evaluated by independent 
      physicians, preoperative and post-operative grading by treating physicians, 
      subjective evaluation of results by the patients themselves, and tabulation and 
      categorization of adverse events (AEs). The SmartXide Quadro variably pulsed CO(2) 
      laser with a microablative DOT scanner, with synchronous delivery of bipolar RF 
      energy emission, proved to be both safe and effective in the treatment of facial 
      rhytides and acne scars. The single treatment protocol was well tolerated and 
      recovery was similar to fractional CO(2) laser skin resurfacing alone. The AEs were 
      minimal and no significant complications occurred.
FAU - Gotkin, Robert H
AU  - Gotkin RH
FAU - Sarnoff, Deborah S
AU  - Sarnoff DS
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Drugs Dermatol
JT  - Journal of drugs in dermatology : JDD
JID - 101160020
SB  - IM
MH  - Acne Vulgaris/complications
MH  - Adult
MH  - Aged
MH  - Cicatrix/etiology/pathology/*therapy
MH  - Combined Modality Therapy
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Laser Therapy/adverse effects/*methods
MH  - Lasers, Gas
MH  - Middle Aged
MH  - Pilot Projects
MH  - Radio Waves/adverse effects
MH  - *Radiofrequency Therapy
MH  - Severity of Illness Index
MH  - *Skin Aging
MH  - Treatment Outcome
EDAT- 2014/03/07 06:00
MHDA- 2014/12/15 06:00
CRDT- 2014/03/06 06:00
PHST- 2014/03/06 06:00 [entrez]
PHST- 2014/03/07 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
AID - S1545961614P0299X [pii]
PST - ppublish
SO  - J Drugs Dermatol. 2014 Mar;13(3):299-304.