PMID- 24600576
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140306
LR  - 20220321
IS  - 2229-516X (Print)
IS  - 2248-9606 (Electronic)
IS  - 2229-516X (Linking)
VI  - 4
IP  - 1
DP  - 2014 Jan
TI  - Significance of serum magnesium levels in critically ill-patients.
PG  - 34-7
LID - 10.4103/2229-516X.125690 [doi]
AB  - BACKGROUND: Magnesium is one of the major electrolytes, deficiency of which is 
      frequently overlooked in critical illness, leading to an adverse clinical outcome 
      if not monitored regularly. SETTINGS AND DESIGN: Single center prospective 
      observational study of 2 years duration. MATERIALS AND METHODS: The subjects 
      studied were monitored for serum magnesium levels 2 times: Day 1 and day 4 of 
      intensive care unit (ICU) admission. Patients were divided into normomagnesemic 
      and hypomagnesemic groups and compared for various parameters. RESULTS: Out of 70 
      critically ill-patients, 50 patients (71.43%) were normomagnesemic, 17 patients 
      (24.29%) were hypomagnesemic and three patients were hypermagnesemic. The stay of 
      the patients in ICU (P > 0.05), Acute Physiology and Chronic Health Evaluation-II 
      (APACHE-II) scoring (P = 0.34) and co-morbidity (P = 0.360) showed an 
      insignificant variation between the two groups. Associated electrolyte 
      abnormalities in hypomagnesemic patients were hypokalemia (58.82%), hyponatremia 
      (47.05%), hypocalcemia (70.58%) and hypophosphatemia (29.41%). About 76.47% of 
      hypomagnesemic population was on magnesium lowering drugs while as 46% of 
      normomagnesemic population was on magnesium lowering drugs (P = 0.030). Mortality 
      of hypomagnesemic group was 74.47% while that of normomagnesemic group was 36% (P 
      = 0.004). CONCLUSION: Hypomagnesemia is a significant electrolyte abnormality in 
      critically ill-patients. Critically ill hypomagnesemic patients have higher 
      mortality than the normomagnesemic patients.
FAU - Zafar, Mir Sadaqat Hassan
AU  - Zafar MS
AD  - Department of Internal and Pulmonary Medicine, Sher-i-Kashmir Institute of 
      Medical Sciences, Srinagar, Jammu and Kashmir, India.
FAU - Wani, Javaid Iqbal
AU  - Wani JI
AD  - Department of Internal and Pulmonary Medicine, Sher-i-Kashmir Institute of 
      Medical Sciences, Srinagar, Jammu and Kashmir, India.
FAU - Karim, Raiesa
AU  - Karim R
AD  - Department of Social and Preventive Medicine, Government Medical College, 
      Srinagar, Jammu and Kashmir, India.
FAU - Mir, Mohammad Muzaffer
AU  - Mir MM
AD  - Department of Clinical Biochemistry, Sher-i-Kashmir Institute of Medical 
      Sciences, Srinagar, Jammu and Kashmir, India.
FAU - Koul, Parvaiz Ahmad
AU  - Koul PA
AD  - Department of Internal and Pulmonary Medicine, Sher-i-Kashmir Institute of 
      Medical Sciences, Srinagar, Jammu and Kashmir, India.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Int J Appl Basic Med Res
JT  - International journal of applied & basic medical research
JID - 101579831
PMC - PMC3931212
OTO - NOTNLM
OT  - Critically ill-patients
OT  - hypomagnesemia
OT  - normomagnesemia
OT  - outcome
COIS- Conflict of Interest: None declared.
EDAT- 2014/03/07 06:00
MHDA- 2014/03/07 06:01
PMCR- 2014/01/01
CRDT- 2014/03/07 06:00
PHST- 2014/03/07 06:00 [entrez]
PHST- 2014/03/07 06:00 [pubmed]
PHST- 2014/03/07 06:01 [medline]
PHST- 2014/01/01 00:00 [pmc-release]
AID - IJABMR-4-34 [pii]
AID - 10.4103/2229-516X.125690 [doi]
PST - ppublish
SO  - Int J Appl Basic Med Res. 2014 Jan;4(1):34-7. doi: 10.4103/2229-516X.125690.