PMID- 24605094
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140624
LR  - 20211021
IS  - 1662-5161 (Print)
IS  - 1662-5161 (Electronic)
IS  - 1662-5161 (Linking)
VI  - 8
DP  - 2014
TI  - The default mode network and social understanding of others: what do brain 
      connectivity studies tell us.
PG  - 74
LID - 10.3389/fnhum.2014.00074 [doi]
LID - 74
AB  - The Default Mode Network (DMN) has been found to be involved in various domains 
      of cognitive and social processing. The present article will review brain 
      connectivity results related to the DMN in the fields of social understanding of 
      others: emotion perception, empathy, theory of mind, and morality. Most of the 
      reviewed studies focused on healthy subjects with no neurological and psychiatric 
      disease, but some studies on patients with autism and psychopathy will also be 
      discussed. Common results show that the medial prefrontal cortex (MPFC) plays a 
      key role in the social understanding of others, and the subregions of the MPFC 
      contribute differently to this function according to their roles in different 
      subsystems of the DMN. At the bottom, the ventral MPFC in the medial temporal 
      lobe (MTL) subsystem and its connections with emotion regions are mainly 
      associated with emotion engagement during social interactions. Above, the 
      anterior MPFC (aMPFC) in the cortical midline structures (CMS) and its 
      connections with posterior and anterior cingulate cortex contribute mostly to 
      making self-other distinctions. At the top, the dorsal MPFC (dMPFC) in the dMPFC 
      subsystem and its connection with the temporo-parietal junction (TPJ) are 
      primarily related to the understanding of other's mental states. As behaviors 
      become more complex, the related regions in frontal cortex are located higher. 
      This reflects the transfer of information processing from automatic to cognitive 
      processes with the increase of the complexity of social interaction. Besides the 
      MPFC and TPJ, the connectivities of posterior cingulate cortex (PCC) also show 
      some changes during tasks from the four social fields. These results indicate 
      that the DMN is indispensable in the social understanding of others.
FAU - Li, Wanqing
AU  - Li W
AD  - State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern 
      Institute for Brain Research, Beijing Normal University Beijing, China ; Center 
      for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal 
      University Beijing, China.
FAU - Mai, Xiaoqin
AU  - Mai X
AD  - Department of Psychology, Renmin University of China Beijing, China.
FAU - Liu, Chao
AU  - Liu C
AD  - State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern 
      Institute for Brain Research, Beijing Normal University Beijing, China ; Center 
      for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal 
      University Beijing, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20140224
PL  - Switzerland
TA  - Front Hum Neurosci
JT  - Frontiers in human neuroscience
JID - 101477954
PMC - PMC3932552
OTO - NOTNLM
OT  - brain connectivity
OT  - default mode network
OT  - empathy
OT  - morality
OT  - social cognition
OT  - theory of mind
EDAT- 2014/03/08 06:00
MHDA- 2014/03/08 06:01
PMCR- 2014/01/01
CRDT- 2014/03/08 06:00
PHST- 2013/06/01 00:00 [received]
PHST- 2014/01/29 00:00 [accepted]
PHST- 2014/03/08 06:00 [entrez]
PHST- 2014/03/08 06:00 [pubmed]
PHST- 2014/03/08 06:01 [medline]
PHST- 2014/01/01 00:00 [pmc-release]
AID - 10.3389/fnhum.2014.00074 [doi]
PST - epublish
SO  - Front Hum Neurosci. 2014 Feb 24;8:74. doi: 10.3389/fnhum.2014.00074. eCollection 
      2014.