PMID- 24605900 OWN - NLM STAT- MEDLINE DCOM- 20140702 LR - 20140430 IS - 1532-4192 (Electronic) IS - 0735-7907 (Linking) VI - 32 IP - 5 DP - 2014 Jun TI - Intensity modulated arc therapy in bilaterally irradiated head and neck cancer: a comparative and prospective multicenter planning study. PG - 159-67 LID - 10.3109/07357907.2014.889705 [doi] AB - A dosimetric comparison was made of Helical Tomotherapy (HT) and Rapid'Arc((R)) (RA) in 115 patients with head and neck carcinoma included in a prospective and multicentric study. HT and RA provided highly conformal plans that easily complied with dose volume constraints for organs at risk. HT reduced high doses to the planning target volumes (PTVs) compared to RA and provided a more homogeneous dose distribution but with an increased Non Tumoral Integral Dose (NTID) than RA. However, the clinical consequences of these dosimetric advantages and disadvantages need further investigation. FAU - Vernat, Stephanie Servagi AU - Vernat SS AD - Department of Radiation Therapy, Besancon University Hospital, Besancon, France1. FAU - Ali, David AU - Ali D FAU - Messina, Caroline AU - Messina C FAU - Pommier, Pascal AU - Pommier P FAU - Dussart, Sophie AU - Dussart S FAU - Puyraveau, Marc AU - Puyraveau M FAU - Viard, Romain AU - Viard R FAU - Lacornerie, Thomas AU - Lacornerie T FAU - Lisbona, Albert AU - Lisbona A FAU - Fenoglietto, Pascal AU - Fenoglietto P FAU - Mazurier, Jocelyne AU - Mazurier J FAU - Garcia, Robin AU - Garcia R FAU - Hangard, Gregory AU - Hangard G FAU - Zefkili, Sophia AU - Zefkili S FAU - Makovicka, Libor AU - Makovicka L FAU - Giraud, Philippe AU - Giraud P LA - eng PT - Comparative Study PT - Journal Article PT - Multicenter Study DEP - 20140307 PL - England TA - Cancer Invest JT - Cancer investigation JID - 8307154 SB - IM MH - Adult MH - Aged MH - Female MH - Head and Neck Neoplasms/*radiotherapy MH - Humans MH - Male MH - Middle Aged MH - Neoplasm Staging MH - Prospective Studies MH - Radiometry/adverse effects/*methods MH - Radiotherapy Dosage MH - Radiotherapy Planning, Computer-Assisted MH - Radiotherapy, Intensity-Modulated/adverse effects/*methods MH - Young Adult EDAT- 2014/03/13 06:00 MHDA- 2014/07/06 06:00 CRDT- 2014/03/11 06:00 PHST- 2014/03/11 06:00 [entrez] PHST- 2014/03/13 06:00 [pubmed] PHST- 2014/07/06 06:00 [medline] AID - 10.3109/07357907.2014.889705 [doi] PST - ppublish SO - Cancer Invest. 2014 Jun;32(5):159-67. doi: 10.3109/07357907.2014.889705. Epub 2014 Mar 7.